Active traders and day traders have many stocks to choose from this Wednesday morning. We are tracking news and  moves in shares of Adobe Systems Incorporated (NASDAQ: ADBE), Oracle Corporation (NASDAQ: ORCL), and Orexigen Therapeutics (NASDAQ: OREX).

Adobe Systems Incorporated (NASDAQ: ADBE) is up 6.4% premarket to $26.22, relative to a 52-week range of $22.67 – $35.99. The company reported 4Q revenue guidance that exceeded market expectations.

Oracle Corporation (NASDAQ: ORCL) is up 5.8% before market open to $26.07, relative to a 52-week range of $24.72 – $36.50. The company reported fiscal Q1 2012 numbers that exceeded market expectations.

Orexigen Therapeutics (NASDAQ: OREX) is up more than 75% premarket to $2.58, relative to a 52-week range of $1.22 – $11.15. The company has reached an agreement with the government to renew testing on their obesity drug.