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The stock market is down Monday, with the Dow Jones Industrial Average down 0.42%, the Nasdaq down 0.18% and the S&P 500 down 0.43%. Today’s winners include a pharmaceutical providing a positive update to one of its drug trials and a medical application manufacturer getting bought. Today’s only loser is a for-profit educator settling a case with Sallie Mae.

Here are Monday’s market winners and loser.

Biggest Winners

Shares of Peregrine Pharmaceuticals, Inc. (NASDAQ: PPHM) are up 82.89% to $2.47 on trading volume of 29.0 million shares. The pharmaceutical company provided strong results of its review of a lung-cancer drug trial, as the company pointed out discrepancies were more limited than the company initially thought. The 52-week high is $5.50.

Shares of Epocrates, Inc. (NASDAQ: EPOC) are up 21.58% to $11.70 on trading volume of 3.5 million shares. AthenaHealth, Inc. (NASDAQ: ATHN) will buy the firm for $11.75 per share, or about $292 million. The 52-week high is $11.97

Biggest Loser

Shares of ITT Educational Services Inc. (NYSE: ESI) are down 15.76% to $16.25 on trading volume of 3.2 million shares. The for-profit educator will pay Sallie Mae $46 million to settle litigation involving student loans. Before Monday, the 52-week low was $16.37.

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