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The stock market is down Monday, with the Dow Jones Industrial Average down 0.09%, the Nasdaq down 0.57% and the S&P 500 down 0.33%. Today’s winners include a smartphone manufacturer gearing up to release a new phone and a biotechnology company optimistic about one of its staple drugs. Today’s sole loser is another smartphone manufacturer that cut orders due to less than expected demand.

These are Monday’s biggest winners and loser.

Biggest Winners

Shares of Research in Motion Limited (NASDAQ: RIMM) are up 6.71% to $14.47 on trading volume of 50.2 million shares. The company’s shares are soaring on industry news, including the fact that Sprint-Nextel Corp. (NYSE: S) would carry its new Blackberry 10. The 52-week high is $17.96.

Shares of Dendreon Corp. (NASDAQ: DNDN) are up 3.41% to $6.38 in trading volume of 8.3 million shares. The biotechnology company’s shares are on optimism for higher demand for Provenge, the company’s prostate-cancer drug. The 52-week high is $17.04.

Biggest Loser

Shares of Apple Inc. (NASDAQ: AAPL) are down 3.14% to $503.94 on trading volume of 10 million shares. Reports of weaker than expected demand for the iPhone have caused the company to cut orders for certain components of the phone. The 52-week low is $419.55.

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