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May 16, 2018: Here are four stocks trading with heavy volume among 74 equities making new 52-week lows in Wednesday’s session. On the NYSE advancers led decliners by about 1.87 to 1 and on the Nasdaq, advancers led decliners by about 1.91 to 1.

Banco Santander SA (NYSE: SAN) dropped about 3.2% Wednesday to post a new 52-week low of $6.27. Shares closed at $6.48 on Tuesday and the stock’s 52-week high is $7.57. Volume of around 7.6 million shares was about 10% above the daily average. The company had no specific news.

Deutsche Bank AG (NYSE: DB) fell by about 2.9% Wednesday to post a new 52-week low of $12.90 after closing at $13.29 on Tuesday. The 52-week high is $20.23. Volume of about 6.3 million was about 40% higher than the daily average of about 4 million. The bank had no specific news.

Cesca Therapeutics Inc. (NASDAQ: KOOL) traded down nearly 34% Wednesday to post a new 52-week low of $0.52 after closing Tuesday at $0.80. The stock’s 52-week high is $6.44. Volume was about 40 times the daily average of around 142,000 shares. The company priced a secondary offering of 9.17 million units at $0.60 per unit of one common share and one common warrant to purchase an additional common share.

Vodafone Group plc (NASDAQ: VOD) traded down about 1.6% Wednesday and posted a new 52-week low of $26.60 after closing Tuesday at $27.04. The stock’s 52-week high is $32.75. Volume totaled around 5.5 million, about 85% higher than the daily average of around 3 million. The company said this morning that long-time CEO Vittorio Colao is retiring and will be replaced by Nick Read.