An estimated 19.9 million students attended the more than 4,600 degree-granting institutions in the United States in the fall 2018 semester, according to the U.S. Department of Education’s National Center for Education Statistics. Enrollment of undergraduate and graduate students has been dropping for years from a fall 2010 peak of 21.0 million, but is expected to climb steadily over the next decade.

Total U.S. postsecondary enrollment last fall declined by 1.8% from the year before, led by a 14.5% drop at four-year for-profit institutions, according to the latest data from the National Student Clearinghouse, a nonprofit that tracks student attendance at degree-granting institutions.

Still even as college attendance has declined, tuition at four-year degree-granting institutions has increased. At some institutions, it has risen to an astronomical degree in a relatively short time. In over a dozen colleges and universities, in-state tuition rose by more than 50%.

To determine the colleges with the largest five-year tuition hikes, 24/7 Wall St. reviewed the latest data from the National Center for Education Statistics. Four-year universities were ranked based on the change in their published in-state tuition from the 2012-13 school year to the 2017-18 school year.

Click here to see the colleges with the biggest tuition hikes.