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Stocks are down Thursday following the news that initial jobless claims rose to 372,000 last week. The Dow Jones is down 0.61%, the Nasdaq is down 0.66% and the S&P 500 is down 0.52%. Today’s market winners include an analyst upgrade and an acquisition, while today’s losers include a retailer who missed earnings and a giant technology company forseeing trouble in the future.

Here are Thursday’s market winners and losers.

Biggest Winners

Shares of Rosetta Genomics, Ltd. (NASDAQ: ROSG) are up 18.81% to 5.62 on trading volume of 4.5 million shares. Flyonthewall.com reports that the company has just received a ‘Buy’ rating from Aegis, and the target price has been set for $16. The 52-week high is $26.70.

Shares of The Hain Celestial Group, Inc. (NASDAQ: HAIN) are up 15.82% to $65.91 on trading volume of 1.9 million shares. The company announced Thursday it plans to buy some food lines from Premier Foods PLC for approximately $318 million. Before Thursday, the 52-week high was $58.31.

Biggest Losers

Shares of Big Lots Inc. (NYSE: BIG) are down 21.16% to $30.62 on trading volume of 4.3 million shares. The company earned 36 cents a share in the second quarter, below the 41 cents a share analysts polled by Reuters were expecting. Before Thursday, the 52-week low was $30.79.

Shares of Hewlett-Packard Company (NYSE: HPQ) are down 6.72% to $17.91 on trading volume of 21.4 million shares. While the company’s third-quarter financials were in line with Wall Street expectations, CEO Meg Whitman hinted to analysts that there would likely be trouble in the personal computer business. The 52-week low is $17.41.

Samuel Weigley

Follow him on Twitter: SWeigley