Nurix Therapeutics

NRIX Q1 2026 Earnings

Reported Apr 8, 2026 at 6:02 AM ET · SEC Source

Q1 26 EPS

$-0.79

MISS 3.32%

Est. $-0.76

Q1 26 Revenue

$6.3M

MISS 56.09%

Est. $14.2M

vs S&P Since Q1 26

+28.0%

BEATING MARKET

NRIX +36.5% vs S&P +8.5%

Market Reaction

Did NRIX Beat Earnings? Q1 2026 Results

Nurix Therapeutics delivered a disappointing fiscal first quarter, missing on both the top and bottom lines as collaboration revenue collapsed 66.1% year-over-year to $6.25 million, well short of the $14.24 million consensus, while its loss per share… Read more Nurix Therapeutics delivered a disappointing fiscal first quarter, missing on both the top and bottom lines as collaboration revenue collapsed 66.1% year-over-year to $6.25 million, well short of the $14.24 million consensus, while its loss per share of $0.79 edged past the $0.76 estimate by 3.32%. The sharp revenue decline was driven primarily by the expiration of the initial research term for certain drug targets under the company's Sanofi collaboration, which had contributed meaningfully to the year-ago period's $18.45 million. Research and development expenses climbed to $84.14 million from $69.66 million as Nurix accelerated enrollment in its Phase 2 DAYBreak CLL-201 pivotal trial and ramped contract manufacturing, widening the net loss to $87.17 million. Despite the headline misses, shares rose roughly 9% in the aftermath, with investors appearing to look past near-term financials toward the planned mid-2026 launch of the global Phase 3 DAYBreak CLL-306 confirmatory trial and a 2026 IND submission targeting autoimmune indications; the company held $540.73 million in cash and equivalents to fund that path.

Key Takeaways

  • Decline in Sanofi collaboration revenue as initial research term for certain drug targets ended
  • Increased R&D spending driven by clinical acceleration of bexobrutideg Phase 2 enrollment and Phase 3 enablement
  • Higher compensation and personnel costs across R&D and G&A functions

NRIX Forward Guidance & Outlook

Nurix plans to initiate the global randomized confirmatory Phase 3 DAYBreak CLL-306 trial by mid-2026 comparing bexobrutideg monotherapy to pirtobrutinib in r/r CLL. The company is targeting a 2026 IND submission for bexobrutideg in inflammatory and autoimmune indications using a new tablet formulation. Updated clinical data from the Phase 1a/1b NX-5948-301 study are expected at medical meetings throughout 2026. Nurix anticipates the achievement of substantial research collaboration milestones throughout the terms of its collaborations with Gilead, Sanofi, and Pfizer.

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NRIX YoY Financials

Q1 2026 vs Q1 2025, source: SEC Filings

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NRIX Revenue by Segment

With YoY comparisons, source: SEC Filings

Q2 25 Q1 26

“Nurix entered 2026 focused on implementing a comprehensive registrational program designed to establish bexobrutideg as a potential best-in-class medicine for patients with chronic lymphocytic leukemia.”

— Arthur T. Sands, Q1 2026 Earnings Press Release