AcelRx Pharmaceuticals Inc. (NASDAQ: ACRX) was downgraded to Hold from Buy and the price target was slashed to $2.25 from $7.00 (versus a $2.15 close) at Jefferies. The firm noted that a one-plus year delay seems likely after the FDA issued a complete response letter for Dsuvia.
Acuity Brands Inc. (NYSE: AYI) was started as Sector Weight at KeyBanc Capital Markets.
Dave & Buster’s Entertainment Inc. (NASDAQ: PLAY) was started with a Buy rating and assigned a $77 price target (versus a $46.34 close) at Longbow Research.
Dollar Tree Inc. (NASDAQ: DLTR) was downgraded to Hold from Buy with an $88 price target (versus a $91.37 close) at Loop Capital.
Harmony Gold Mining Co. Ltd. (NASDAQ: HMY) was downgraded to Sell from Hold at Deutsche Bank.
Hostess Brands Inc. (NASDAQ: TWNK) was downgraded to Sell from Neutral with an $11 price target (versus a $13.43 close) at UBS.
HubSpot Inc. (NYSE: HUBS) was downgraded to Sector Weight from Overweight at KeyBanc Capital Markets.
Mastercard Inc. (NYSE: MA) was started as Overweight and assigned a $165 price target (versus a $146.74 close) at Stephens.
Newfield Exploration Co. (NYSE: NFX) Cut to Market Perform From Outperform with a $32 price target (versus a $29.78 close) at BMO Capital Markets.
Newlink Genetics Corp. (NASDAQ: NLNK) was started as Buy with a $22 price objective (versus an $11.25 close) at Merrill Lynch. The firm believes that NewLink’s Indoximod is undervalued after its Phase 2 efficacy is in line with competition and could become a backbone therapy for cancer treatment if successful in development.
NOW Inc. (NYSE: DNOW) was downgraded to Neutral from Outperform with a $15 price target (versus a $13.19 close) at Robert W. Baird.
OneMain Holdings Inc. (NYSE: OMF) was reiterated as Buy and the price objective was raised to $35 (versus a $30.92 close) at Merrill lynch, noting that the current buyout speculation is fueling a lift for OneMain.
PayPal Holdings Inc. (NASDAQ: PYPL) was reiterated as Buy and the price target was raised to $80 from $70 (versus a $68.86 close) at Jefferies. The firm feels that “Pay with Venmo” can add significantly to earnings in 2020.
RPC Inc. (NYSE: RES) was downgraded to Neutral from Outperform at Credit Suisse, on a valuation downgrade.
SecureWorks Corp. (NASDAQ: SCWX) was downgraded to Underweight from Equal Weight at Barclays.
Spark Therapeutics Inc. (NASDAQ: ONCE) was reiterated as Buy with a $95 price target (versus an $86.20 close) at Jefferies.
Williams-Sonoma Inc. (NYSE: WSM) was started as Hold with a $54 price target at Stifel.
Thursday’s top analyst upgrades and downgrades included Ardelyx, Juniper Networks, Kroger, Phillips 66, Square, Transocean, Walmart and many more.