ADC Therapeutics (ADCT) Q1 2026 Earnings
How Did ADCT Stock React to Q1 2026 Earnings?
S&P 500 over the same 30 days: +5.44%.
Did ADCT Beat Earnings? Q1 2026 Results
Yes. ADC Therapeutics reported Q1 2026 earnings of $-0.13 a share on May 4, 2026, beating the $-0.20 consensus estimate by 35.5%. Revenue was $20.9M against a $20.0M estimate.
ADC Therapeutics delivered a stronger-than-expected first quarter for fiscal 2026, posting a loss of $0.13 per share against a consensus estimate of $0.20, a beat of 35.55%, while revenue of $20.85 million edged past the $19.99 million analyst forecast by 4.32%. Total revenue fell 9.5% year over year, largely because the prior-year period included a one-time partner milestone that inflated license revenues; stripping that out, net product revenues for ZYNLONTA grew 15% to $20.03 million, reflecting higher pricing and stronger unit volumes. The narrower loss was also driven by a $9.05 million reduction in R&D expenses as discontinued programs and completed IND-enabling work lowered external costs. Management maintained its cash runway guidance of at least into 2028, with $231.01 million on hand, and investors are closely watching for topline data from the LOTIS-5 Phase 3 confirmatory trial, expected by the end of June, which could support an sBLA submission before year-end and potentially unlock a significantly broader addressable market for ZYNLONTA across B-cell malignancies.
- ZYNLONTA product revenue growth driven by higher volume and pricing
- R&D expense reduction of $9 million due to discontinued programs and completed IND-enabling activities
- Personnel cost reallocation from R&D to commercial manufacturing and selling activities
“During the first quarter, we continued to build momentum across our ZYNLONTA program. Looking ahead, we have multiple near-term catalysts, including topline results from LOTIS-5 anticipated in the second quarter, full results expected from both LOTIS-5 and LOTIS-7 by year-end, as well as additional updates from the investigator-initiated studies in indolent lymphomas ahead. We believe that we are well-positioned to expand ZYNLONTA's role across B-cell malignancies, accelerating our expected growth trajectory starting in 2027.”
ADC Therapeutics CEO, on the earnings call
What Was ADC Therapeutics's Outlook in Q1 2026?
ADC Therapeutics expects LOTIS-5 Phase 3 topline results in Q2 2026, with full results from both LOTIS-5 and LOTIS-7 anticipated by year-end 2026. If LOTIS-5 is positive, the company intends to submit an sBLA to the FDA before year-end, targeting potential compendia inclusion in H1 2027 and confirmatory approval in 2L+ DLBCL thereafter. Investigator-initiated trial data in follicular lymphoma and marginal zone lymphoma are expected between late 2026 and mid-2027. The company projects cash runway at least into 2028 and anticipates accelerating its growth trajectory starting in 2027.
ADCT YoY Financials
| Metric | Q1 2026 | Q1 2025 | Year over year |
|---|---|---|---|
| Revenue | $20.9M | $23.0M | −9.5% |
| Gross Profit | $17.2M | $21.0M | −17.8% |
| Operating Income | −$25.2M | −$22.7M | +11.3% |
| Net Income | −$33.0M | −$28.8M | +14.6% |
ADCT Revenue by Segment
Figures from SEC filings and company reports. Not investment advice.