Huge Insider Buying Now at This Insurance Giant and 2 Biotechs
Alumis, Aktis Oncology, and W.R. Berkley saw the most prominent insider buying of the past week. There were a handful of other notable purchases as well.
Headquartered in South San Francisco, CA Fiscal year ends December NASDAQ: ALMS alumis.com
Alumis Inc. is a late-stage biopharmaceutical company developing next-generation targeted therapies for immune-mediated diseases. The company leverages a proprietary data analytics platform and precision approach to develop a pipeline of oral tyrosine kinase 2 (TYK2) inhibitors. Its lead candidate, envudeucitinib (formerly ESK-001), is in late-stage clinical development for systemic immune-mediated disorders including moderate-to-severe plaque psoriasis (NDA submission planned Q4 2026) and systemic lupus erythematosus (Phase 2b). The company is also developing A-005, a CNS-penetrant TYK2 inhibitor initially focused on Parkinson's disease and additional neuroinflammatory and neurodegenerative indications. Alumis generates limited collaboration revenue from a licensing agreement with Kaken Pharmaceutical Co., Ltd. The company merged with ACELYRIN, Inc. in 2025, and is exploring strategic alternatives for its lonigutamab program. Updated
Alumis, Aktis Oncology, and W.R. Berkley saw the most prominent insider buying of the past week. There were a handful of other notable purchases as well.
Alumis Inc. is a late-stage biopharmaceutical company developing next-generation targeted therapies for immune-mediated diseases. The company leverages a proprietary data analytics platform and precision approach to develop a pipeline of oral tyrosine kinase 2 (TYK2) inhibitors.
The Wall Street consensus 12-month price target for ALMS is $32.12.