Beam Therapeutics

Beam Therapeutics (BEAM) Q4 2025 Earnings

Reported Feb 24, 2026 at 7:05 AM ET · SEC Source

Q4 25 EPS

$2.33

BEAT +308.97%

Est. $-1.12

Q4 25 Revenue

$114.1M

BEAT +781.34%

Est. $12.9M

vs S&P Since Q4 25

+4.1%

BEATING MARKET

BEAM +11.5% vs S&P +7.4%

Full Year 2025 Results

FY 25 EPS

$-0.81

BEAT +81.08%

Est. $-4.28

FY 25 Revenue

$139.7M

BEAT +262.99%

Est. $38.5M

Market Reaction

Did BEAM Beat Earnings? Q4 2025 Results

Beam Therapeutics delivered a striking earnings beat in Q4 2025, posting adjusted EPS of $2.33 against a consensus estimate of negative $1.01, a positive surprise of 330.69%, while revenue of $114.11 million cleared the $12.86 million consensus by 78… Read more Beam Therapeutics delivered a striking earnings beat in Q4 2025, posting adjusted EPS of $2.33 against a consensus estimate of negative $1.01, a positive surprise of 330.69%, while revenue of $114.11 million cleared the $12.86 million consensus by 787.07% and rose 279.5% from the year-ago quarter. The headline driver was a $255.15 million gain on the sale of an equity method investment, which pushed the company to GAAP net income of $244.30 million compared to a net loss of $90.35 million a year earlier; absent that one-time item, Beam would have remained in the red. Revenue itself was propelled by Pfizer's opt-in to an exclusive worldwide license for a liver-targeted development candidate, concluding a four-year research collaboration. Looking ahead, Beam extended its cash runway into mid-2029, supported by a $1.25 billion year-end cash position and a new $500.00 million credit facility with Sixth Street, with key catalysts including a potential BLA submission for risto-cel in sickle cell disease as early as year-end 2026 and updated BEAM-302 data expected by the close of Q1 2026.

Key Takeaways

  • Gain on sale of equity method investment of $255.1 million drove Q4 net income
  • License and collaboration revenue of $114.1 million in Q4 2025 versus $30.1 million in Q4 2024, reflecting Pfizer collaboration activities
  • Strong cash position of $1.25 billion at year-end bolstered by collaboration payments and financing
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BEAM YoY Financials

Q4 2025 vs Q4 2024, source: SEC Filings

“In 2025, we established base editing as a best-in-class technology for genetic medicine, with positive proof-of-concept data and regulatory and clinical development paths to approval across multiple high-value programs.”

— John Evans, Q4 2025 Earnings Press Release