Companies /Healthcare

Charles River Laboratories International Inc

NYSE: CRL Diagnostics & Research
$293.16
▲ $1.40 (+0.48%) today
Markets closed · 4:26pm ET

Q2 2025 Earnings

Reported Aug 6, 2025, 7:08am ET · SEC source
$3.12
Beat +24.59%
EPS · est. $2.50
$1.0B
Beat +4.78%
Revenue · est. $985.1M
+5.2%
Beating market
CRL vs S&P since report
6 quarters
Consecutive EPS beats

Market Reaction

% change · around the report
−12%−6%0Aug 6Aug 7report 7:08am ETearnings+0.1%−16.4%
−12%−6%0Aug 6Aug 7earnings+0.1%−16.4%
CRL −16.4%S&P 500 +0.1%
−12%−6%0Aug 6Aug 7report 7:08am ETearnings+1.2%−16.4%
−12%−6%0Aug 6Aug 7earnings+1.2%−16.4%
CRL −16.4%NASDAQ +1.2%
−12%−6%0Aug 5Aug 13report 7:08am ETearnings+2.4%−11.3%
−12%−6%0Aug 5Aug 13earnings+2.4%−11.3%
CRL −11.3%S&P 500 +2.4%
−12%−6%0Aug 5Aug 13report 7:08am ETearnings+3.3%−11.3%
−12%−6%0Aug 5Aug 13earnings+3.3%−11.3%
CRL −11.3%NASDAQ +3.3%
−10.25%
Day of report
−0.37%
Next session
+3.11%
One week
+7.76%
30 days

S&P 500 over the same 30 days: +2.54%.

Did CRL Beat Earnings? Q2 2025 Results

Charles River Laboratories delivered a standout second quarter, posting non-GAAP EPS of $3.12 against a consensus estimate of $2.50, a beat of 24.59%, while revenue of $1.03 billion edged 0.6% higher year-over-year and cleared the $985.08 million consensus by 4.78%. The stronger-than-expected results were driven in large part by dramatic margin expansion in the Manufacturing segment, where non-GAAP operating margins surged to 32.8% from 26.6% a year ago on commercial CDMO revenue, while restructuring savings lifted profitability across all three divisions. Adding further lift to investor sentiment, the company announced it had been cleared in a DOJ grand jury investigation into its non-human primate supply chain, removing a legal overhang that had weighed on the stock for years. Management raised full-year 2025 non-GAAP EPS guidance to a range of $9.90 to $10.30 from $9.30 to $9.80, and narrowed its revenue outlook, as <a href="https://247wallst.com/investing/2025/07/31/stock-market-live-july-31-sp-500-voo-rises-on-positive-china-earnings-news/">broader market tailwinds</a> coincided with CEO James Foster signaling that biopharmaceutical client demand is gradually stabilizing.

Key Takeaways
  • Non-GAAP operating margin improvement across all three segments
  • Favorable results in DSA segment drove better-than-expected performance
  • RMS organic revenue growth of 2.3% driven by large research models and GEMS/Insourcing Solutions
  • Manufacturing organic growth of 2.9% driven by Microbial Solutions business
  • Manufacturing non-GAAP margin expansion to 32.8% driven by commercial CDMO client revenue and payments
  • Cost savings from restructuring initiatives benefited margins across segments
  • Lower diluted shares outstanding from stock repurchase program boosted non-GAAP EPS
  • Foreign currency translation added 1.2% to reported revenue

“We are continuing to see clear signs that the biopharmaceutical demand is stabilizing, and in this environment, we are making gradual progress to return to organic revenue growth. This progress was demonstrated in our solid second-quarter financial performance, driven principally by favorable results in our DSA segment.”

Charles River Laboratories CEO, on the earnings call

Forward Guidance & Outlook

Charles River raised its full-year 2025 guidance. Reported revenue growth is now expected to decline 2.5% to 0.5% (previously a decline of 5.5% to 3.5%), with organic revenue expected to decline 3.0% to 1.0% (previously 4.5% to 2.5%). The favorable impact of foreign exchange is approximately 0.5%. GAAP EPS is expected at $4.25 to $4.65 (previously $4.35 to $4.85). Non-GAAP EPS guidance was raised to $9.90 to $10.30 (from $9.30 to $9.80). The improved outlook primarily reflects better-than-expected Q2 results, particularly in the DSA segment, and a more favorable foreign exchange impact. The company noted that biopharmaceutical demand is stabilizing and it is making gradual progress toward returning to organic revenue growth.

CRL YoY Financials

Q2 2025 vs Q2 2024 · SEC filings Q2 2024 Q2 2025
$0$300.0M$600.0M$900.0M$1.0B$1.0BRevenue$151.6M$100.1MOperating Income$90.0M$52.3MNet Income
$0$300.0M$600.0M$900.0MRevenueOperating IncomeNet Income

CRL Revenue by Segment

Discovery and Safety Assessment$618.0M−1.5%
Research Models and Services$213.3M+3.3%
Manufacturing Solutions$200.8M+4.4%

Figures from SEC filings and company reports. Not investment advice.