Intellia Therapeutics Inc
Q2 2026 Earnings
Market Reaction
Did NTLA Beat Earnings? Q2 2026 Results
Intellia Therapeutics delivered a mixed second quarter for 2026, missing on both the top and bottom lines even as a landmark clinical readout underscored the promise of its gene editing platform. The company posted a GAAP net loss of $0.80 per share, falling short of the $0.78 consensus by 1.95%, snapping a streak of six consecutive quarterly EPS beats. Collaboration revenue tumbled 46.2% year over year to $7.66 million, coming in well below the $12.98 million analysts had expected, as reduced contributions from Regeneron on the nex-z program weighed heavily on the top line. The headline story, however, was the Phase 3 HAELO trial for lonvoguran ziclumeran in hereditary angioedema, which demonstrated an 87% reduction in attacks versus placebo and was published in the New England Journal of Medicine. G&A expenses climbed to $37.82 million from $27.21 million a year ago, reflecting aggressive commercial buildout ahead of a planned U.S. launch in the first half of 2027, contingent on BLA acceptance expected later this year. Intellia ended the quarter with $628.35 million in cash, providing runway into at least 2028.
- Positive Phase 3 HAELO data for lonvo-z driving regulatory and commercial momentum
- R&D expense reduction driven by lower external costs on lead development programs and reduced stock-based compensation
- G&A expense increase driven by commercial infrastructure buildout for anticipated lonvo-z launch
- Collaboration revenue decline primarily due to reduced revenue from Regeneron
“The second quarter was a momentous period for Intellia highlighted by the positive Phase 3 HAELO clinical trial results we reported for lonvo-z in hereditary angioedema. These data serve as strong validation for in vivo gene editing and lonvo-z's potential to transform the treatment paradigm for patients who are burdened by this disease.”
Intellia Therapeutics CEO, on the earnings call
Forward Guidance & Outlook
Intellia expects FDA acceptance of its BLA submission for lonvo-z in the second half of 2026, with a planned U.S. commercial launch in the first half of 2027. The company expects to complete MAGNITUDE-2 enrollment for nex-z in ATTRv-PN in the second half of 2026. Cash, cash equivalents and marketable securities of approximately $628 million are expected to fund operations at least into 2028 and well beyond lonvo-z's anticipated U.S. commercial launch, excluding potential commercial revenues from lonvo-z.
NTLA YoY Financials
NTLA Revenue by Segment
Figures from SEC filings and company reports. Not investment advice.