Schrodinger

SDGR Q2 2025 Earnings

Reported Aug 6, 2025 at 4:07 PM ET · SEC Source

Q2 25 EPS

$-0.65

MISS 1.56%

Est. $-0.64

Q2 25 Revenue

$54.8M

BEAT +5.35%

Est. $52.0M

vs S&P Since Q2 25

-40.8%

TRAILING MARKET

SDGR -24.8% vs S&P +16.0%

Market Reaction

Did SDGR Beat Earnings? Q2 2025 Results

Schrödinger delivered a mixed second quarter, clearing Wall Street's revenue bar while falling just short on the bottom line, as the computational drug discovery company navigated a period of meaningful operational transition. Revenue rose 15.7% year… Read more Schrödinger delivered a mixed second quarter, clearing Wall Street's revenue bar while falling just short on the bottom line, as the computational drug discovery company navigated a period of meaningful operational transition. Revenue rose 15.7% year-over-year to $54.76 million, beating the $51.98 million consensus by 5.35%, lifted by a 15% gain in software revenue to $40.54 million and a 19% jump in drug discovery revenue to $14.21 million. Yet the earnings picture was cloudier, with a non-GAAP loss of $0.65 per share missing the $0.64 consensus estimate, even as the GAAP net loss narrowed to $43.17 million from $54.05 million a year ago. The most pressing story, however, came from the pipeline, where the company has since discontinued its CDC7 inhibitor SGR-2921 following patient deaths in a Phase 1 trial. Management maintained full-year software revenue growth guidance of 10%-15% and drug discovery revenue of $45 to $50 million, while guiding operating expenses lower than 2024, aided in part by a completed 7% workforce reduction expected to generate roughly $30 million in annualized savings.

Key Takeaways

  • Software revenue growth driven by increases in hosted contract revenue and contribution revenue
  • Drug discovery revenue increased 19% year-over-year
  • Other income of $10 million including favorable fair value changes in equity investments
  • Lower R&D expenses contributed to reduced operating expenses
24/7 Wall St

SDGR YoY Financials

Q2 2025 vs Q2 2024, source: SEC Filings

24/7 Wall St

SDGR Revenue by Segment

With YoY comparisons, source: SEC Filings

Q2 25 Q1 26

“In a highly dynamic macroenvironment, our ability to deliver solid second quarter results and maintain our 2025 revenue growth guidance is a testament to our strong customer relationships and the demand for proven computational technologies to accelerate molecular discovery. In addition to progressing several collaborative programs in our pipeline, we achieved an important milestone with the presentation of encouraging initial data for our MALT1 inhibitor, SGR-1505, and we expect to report initial data from our other two clinical programs in the fourth quarter.”

— Ramy Farid, Q2 2025 Earnings Press Release