Tempus AI Drops 15.3% After-Hours, Shedding About $2 Billion

As seen on the 24/7 Wall St. homepage on October 6, 2026.

TEM Tempus AI

After-hours

5:00pm ET

$71.98

-15.32% open $85.00

A 15.3% slide to $71.98 wipes roughly $2 billion off a $12.6 billion AI diagnostics name in a single session. Moves this big reset the whole trading range, so watch where it opens next.

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Tempus AI shed roughly 15.3% in after-hours trading, closing at $71.98 after opening the session at $85.00.

The decline strips approximately $2 billion from what was a $12.6 billion AI diagnostics company, resetting the price levels traders had used as reference points.

The stock stabilized in a tight band near $72, so the heaviest selling eased without reversing. Where it opens in the next regular session is the first real test of whether buyers see value here.

Tempus AI operates in AI-driven diagnostics, where valuations move sharply on sentiment shifts alone. Anyone holding or sizing a position should note that the new opening price sets a fresh baseline for how the market values the company.

Sources

TEM company overview

Mentioned: TEM

Related Market Updates

Biggest movers · At the close 4:10pm ET

Gainers

CIENCiena$445.37+14.3%
CEGConstellation Energy$300.52+12.3%
FNFabrinet$488.18+7.6%
NBISNebius Group$250.1+7.5%
ALABAstera Labs$388.9+7.3%

Losers

TEMTempus AI$71.68-14.2%
STXSeagate Technology$806.34-9.1%
MRNAModerna$187.05-8.0%
APPSDigital Turbine$10.48-6.6%
SKHYSK hynix Inc.$182.3-6.5%

Nearly 29 points of spread separated the top and bottom of the board at Monday's close, with Ciena up 14.29% to $445.37 and Tempus AI down 14.21% to $71.68. Four of the five leaders sit in AI infrastructure names.

TEM Tempus AI

Regular session

12:40pm ET

$74.22

-12.69% open $85.00

A 12.7% intraday slide to $74.22 strips roughly an eighth off a $13 billion market cap in a single session. Whether the $85 open gets reclaimed is the level to keep an eye on.

Biggest movers · At the close Oct 5, 4:10pm ET

Gainers

PBR-APetrobras$22.12+12.8%
PBRPetrobras$24.17+11.6%
MELIMercadoLibre$1,864.06+9.9%
TEMTempus AI$83.63+9.1%
FUTUFutu Holdings$110.05+7.7%

Losers

OPENOpendoor Technologies$2.33-4.7%
NBISNebius Group$232.87-4.1%
BMYBristol Myers Squibb$58.81-3.8%
NOKNokia$10.22-3.6%
GLWCorning$158.53-3.5%

Both Petrobras lines closed double digits higher, the only names in a 383-stock board to do it. MercadoLibre and Tempus AI each added more than 9%, while the worst loser gave up under 5%, so the upside skew was lopsided.

Biggest movers · At the close Oct 1, 4:10pm ET

Gainers

ACNAccenture$211.97+15.6%
SNPSSynopsys$490.81+12.8%
COHRCoherent$318.52+10.7%
AAOIApplied Optoelectronics$107.16+8.0%
LITELumentum$1,043.95+7.5%

Losers

AMCAMC Entertainment$2.75-8.2%
TEMTempus AI$76.51-6.6%
BRKRBruker$61.76-4.6%
DHRDanaher$211.34-4.6%
NWGNatWest Group$17.36-4.3%

Three names in our 383-stock board closed with double-digit gains, led by Accenture's 15.6% jump to $211.97, a move that size is rare for a mega-cap consultant. The downside was far tamer, with AMC's 8.2% slide the worst of it.

Biggest movers · At the close Sep 24, 4:11pm ET

Gainers

BRKRBruker$64.13+7.5%
TEMTempus AI$82.15+7.3%
IONQIonQ$45.01+5.8%
AFRMAffirm$71.54+5.1%
METAMeta$778.35+4.6%

Losers

ARMArm$304.35-8.5%
APPSDigital Turbine$10.94-5.2%
GPROGoPro$1.25-4.6%
GMGeneral Motors$80.22-4.2%
SNDKSanDisk$1,753.24-3.5%

Arm's 8.5% slide was the deepest move in a 111-stock priority list at Wednesday's close, with Bruker leading the upside at 7.5%.

Biggest movers · At the close Sep 17, 4:10pm ET

Gainers

TEMTempus AI$80.08+14.5%
SMRNuScale Power$9.15+10.2%
IONQIonQ$40.31+9.4%
SMCISuper Micro Computer$40.28+9.3%
ALABAstera Labs$293.29+9.0%

Losers

DKNGDraftKings$22.54-7.4%
FUBOfuboTV$9.93-6.4%
CRWVCoreWeave$80.15-3.9%
SPOTSpotify$529.96-3.2%
AXONAxon Enterprise$453.59-3.2%

Tempus AI closed 14.46% higher, the biggest move in a 111-name priority list where four other gainers ran 9% or better. The downside was far tamer: DraftKings led decliners at 7.38%, and nothing else lost more than 6.4%.

Biggest movers · At the close Sep 15, 4:10pm ET

Gainers

TEMTempus AI$68.74+10.5%
BRKRBruker$55.97+6.3%
QCOMQualcomm$187.79+4.2%
SSentinelOne$23.47+3.8%
RBRKRubrik$103.47+3.3%

Losers

AXONAxon Enterprise$444.7-9.3%
CAVACava$49.8-9.3%
CLOVClover Health$4.64-9.1%
FUBOfuboTV$10.9-8.2%
OPENOpendoor Technologies$2.65-5.2%

Tempus AI closed the session up 10.5%, the only double-digit move among 111 tracked names. The downside was deeper and broader: Axon, Cava and Clover Health all gave up more than 9%.

Biggest movers · At the close Aug 24, 4:10pm ET

Gainers

AMCAMC Entertainment$2.71+6.1%
EXPEExpedia$337.61+5.0%
SNAPSnap$5.47+4.3%
BROSDutch Bros$51.84+4.0%
ULTAUlta Beauty$540.82+3.7%

Losers

AAOIApplied Optoelectronics$110.34-11.6%
HIMSHims & Hers$30.91-8.5%
TEMTempus AI$66.83-8.1%
IONQIonQ$41.45-7.6%
SNDKSanDisk$1,491.74-6.5%

The damage at Monday's close ran deeper than the gains: Applied Optoelectronics shed 11.6% while the best performer, AMC Entertainment, managed 6.08%. Four of the five worst names lost more than 7% in a single session.

Biggest movers · At the close Aug 21, 4:10pm ET

Gainers

FUTUFutu Holdings$123.72+9.8%
TEMTempus AI$72.55+8.8%
IONQIonQ$45.16+8.7%
RIVNRivian$17.11+6.8%
HIMSHims & Hers$33.74+5.9%

Losers

CIFRCipher Mining$15.76-8.4%
AAOIApplied Optoelectronics$124.48-3.6%
FUBOfuboTV$10.25-3.2%
ARMArm$243.16-3.0%
IRENIren$41.32-3.0%

Futu Holdings closed up 9.75%, the biggest move in a 110-stock priority list where five names finished higher by 5% or more. The downside was far tamer: only Cipher Mining lost more than 4%.

Biggest movers · At the close Aug 20, 4:10pm ET

Gainers

MARAMarathon Digital$10.94+13.4%
TEMTempus AI$66.48+8.5%
AAOIApplied Optoelectronics$129.38+5.9%
FUBOfuboTV$10.79+4.4%
CIFRCipher Mining$16.58+4.3%

Losers

WMTWalmart$103.1-9.8%
IQiQIYI$1.04-8.0%
ACHRArcher Aviation$6.04-6.4%
UPSTUpstart$28.82-5.8%
IONQIonQ$41.39-4.5%

A near 10% single-day drop in a mega-cap retailer like Walmart, closing at $103.10, is the kind of move that rarely shows up on a leaderboard next to small caps. Marathon Digital ran the other way, up 13.37%, with Cipher Mining also in the green.

Biggest movers · At the close Aug 19, 4:10pm ET

Gainers

TEMTempus AI$60.68+22.9%
HIMSHims & Hers$30.74+12.2%
GPROGoPro$0.64+7.5%
SMRNuScale Power$9.24+6.9%
UPSTUpstart$30.97+6.4%

Losers

IQiQIYI$1.12-9.2%
DOCNDigitalOcean$116.16-7.3%
DELLDell Technologies$436.24-6.9%
APPSDigital Turbine$11.32-6.6%
AAOIApplied Optoelectronics$122.85-6.5%

Tempus AI ended the day up 22.93% at $60.68, the standout in a 110-name priority list where nothing else gained more than 13%. Hardware and infrastructure names took the other side, with Dell shedding 6.92% to $436.24.