Headquartered in Waterloo Exchange, Dublin Fiscal year ends December NASDAQ: JAZZ jazzpharma.com
Jazz Pharmaceuticals plc is a global biopharmaceutical company focused on rare diseases, often where patients have limited or no therapeutic options.
Its commercial portfolio spans three areas:
- **Sleep medicine:** Xywav, a low-sodium oxybate for narcolepsy and idiopathic hypersomnia, and Xyrem.
- **Epilepsy:** Epidiolex/Epidyolex (cannabidiol).
- **Oncology/hematology:** Zepzelca (lurbinectedin) for small-cell lung cancer; Ziihera (zanidatamab-hrii), recently approved for first-line HER2+ gastroesophageal adenocarcinoma; Modeyso (dordaviprone), launched in August 2025; Rylaze/Enrylaze; Defitelio/defibrotide; and Vyxeos.
The company also earns royalty revenue on authorized generic high-sodium oxybate. In September 2026 it acquired Actio Biosciences, adding ABS-1230 (JZP6979), a potential first-in-class precision therapy for KCNT1-related epilepsy, to its rare epilepsy pipeline. Jazz runs R&D laboratories and manufacturing facilities in multiple countries. Updated
A $754 million acquired IPR&D charge from the Actio deal cut adjusted EPS by $11.03 a share, so the headline loss masks a quarter that beat. Revenue topped expectations and management raised full-year guidance.
One of Wall Street’s major firms just put its stamp of approval on a specialty pharma name that has been quietly rallying. UBS upgraded Jazz Pharmaceuticals (NASDAQ:JAZZ | JAZZ Price Prediction) to…
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Jazz Pharmaceuticals plc is a global biopharmaceutical company focused on rare diseases, often where patients have limited or no therapeutic options.
24/7 Wall St.'s 12-month price target for JAZZ is $282.66, rated Buy. The Wall Street consensus target is $296.27. JAZZ price prediction →
