Alkermes

Alkermes (ALKS) Q2 2025 Earnings

Reported Jul 29, 2025 at 7:05 AM ET · SEC Source

Q2 25 EPS

$0.52

BEAT +37.93%

Est. $0.38

Q2 25 Revenue

$390.7M

BEAT +14.46%

Est. $341.3M

vs S&P Since Q2 25

+86.0%

BEATING MARKET

ALKS +103.2% vs S&P +17.2%

Market Reaction

Did ALKS Beat Earnings? Q2 2025 Results

Alkermes delivered a standout second quarter, posting earnings per share of $0.52 against a consensus estimate of $0.38, a beat of 37.93%, while revenue of $390.66 million cleared expectations by 14.46% despite slipping 2.1% year-over-year. The headl… Read more Alkermes delivered a standout second quarter, posting earnings per share of $0.52 against a consensus estimate of $0.38, a beat of 37.93%, while revenue of $390.66 million cleared expectations by 14.46% despite slipping 2.1% year-over-year. The headline revenue decline masked a genuinely strong underlying performance: total proprietary net sales climbed 14% to $307.20 million, led by 18% growth in both ARISTADA and LYBALVI and a 9% gain in VIVITROL, with the top-line softness driven almost entirely by the expiration of the INVEGA SUSTENNA royalty in August 2024, which pulled manufacturing and royalty revenues down to $83.40 million from $129.90 million a year ago. Higher R&D investment of $77.37 million, up sharply from $59.65 million, reflected accelerating spend behind alixorexton, the company's narcolepsy candidate that produced positive Phase 2 topline results in the Vibrance-1 study. Looking ahead, Alkermes reiterated its full-year 2025 guidance, targeting total revenues of $1.34 billion to $1.43 billion and GAAP net income of $175 million to $205 million, with a global Phase 3 program for alixorexton expected to begin following Vibrance-2 topline data this fall.

Key Takeaways

  • Strong growth across all three proprietary products (VIVITROL, ARISTADA, LYBALVI)
  • ARISTADA revenue included approximately $11.0M of gross-to-net favorability from Medicaid utilization adjustments
  • VIVITROL revenue included approximately $9.0M of gross-to-net favorability from Medicaid utilization adjustments
  • LYBALVI total prescriptions grew 22% year-over-year
  • Decline in manufacturing and royalty revenues due to expiration of royalty on U.S. net sales of INVEGA SUSTENNA in August 2024
24/7 Wall St

ALKS YoY Financials

Q2 2025 vs Q2 2024, source: SEC Filings

24/7 Wall St

ALKS Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“Our second quarter results reflect strong performance across all three of our proprietary products and robust profitability and cash flow generation.”

— Richard Pops, Q2 2025 Earnings Press Release