Alkermes

Alkermes (ALKS) Q4 2025 Earnings

Reported Feb 25, 2026 at 7:05 AM ET · SEC Source

Q4 25 EPS

$0.29

MISS 35.28%

Est. $0.45

Q4 25 Revenue

$384.5M

BEAT +0.80%

Est. $381.5M

vs S&P Since Q4 25

+65.9%

BEATING MARKET

ALKS +73.9% vs S&P +8.0%

Full Year 2025 Results

FY 25 EPS

$1.43

MISS 25.85%

Est. $1.93

FY 25 Revenue

$1.48B

BEAT +0.22%

Est. $1.47B

Market Reaction

Did ALKS Beat Earnings? Q4 2025 Results

Alkermes delivered a mixed fourth quarter for 2025, beating on revenue while falling well short on the bottom line, as the expiration of its lucrative INVEGA SUSTENNA royalty continued to weigh on results. The Dublin-based biopharmaceutical company p… Read more Alkermes delivered a mixed fourth quarter for 2025, beating on revenue while falling well short on the bottom line, as the expiration of its lucrative INVEGA SUSTENNA royalty continued to weigh on results. The Dublin-based biopharmaceutical company posted Q4 revenue of $384.55 million, edging past the $381.30 million consensus by 0.85%, though that figure still represented a 10.6% decline from the year-ago period when royalty income padded the top line. Earnings per share came in at $0.29, missing the $0.41 analyst consensus by 29.27%, with GAAP net income falling sharply to $49.34 million from $146.50 million in Q4 2024. Bright spots included LYBALVI, whose revenues of $94.14 million grew 22% year over year, helping proprietary product net sales climb to $315.49 million. The bigger story, however, is the February 2026 close of the $2.3 billion Avadel Pharmaceuticals acquisition, which adds narcolepsy drug LUMRYZ to the portfolio and underpins 2026 revenue guidance of $1.73 billion to $1.84 billion, even as acquisition-related charges are expected to push the company to a GAAP net loss of $115 million to $135 million next year.

Key Takeaways

  • LYBALVI revenue growth of 22% in Q4 with prescriptions up 25% year-over-year
  • Proprietary product net sales increased approximately 9% year-over-year in FY 2025
  • Disciplined expense management contributing to strong profitability and cash flow
  • Expiration of INVEGA SUSTENNA royalty in August 2024 reduced manufacturing & royalty revenues
24/7 Wall St

ALKS YoY Financials

Q4 2025 vs Q4 2024, source: SEC Filings

24/7 Wall St

ALKS Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“Enabled by our strong operational and financial performance in 2025, Alkermes enters 2026 in a position of great strength, both financially and in terms of the opportunity to create value for shareholders through the development of important new medicines with significant market potential.”

— Richard Pops, Q4 2025 Earnings Press Release