BridgeBio Pharma

BBIO Q3 2025 Earnings

Reported Oct 29, 2025 at 4:02 PM ET · SEC Source

Q3 25 EPS

$-0.95

MISS 22.31%

Est. $-0.78

Q3 25 Revenue

$120.7M

BEAT +14.23%

Est. $105.7M

vs S&P Since Q3 25

-1.1%

TRAILING MARKET

BBIO +6.7% vs S&P +7.9%

Market Reaction

Did BBIO Beat Earnings? Q3 2025 Results

BridgeBio Pharma delivered a mixed Q3 2025 report, posting revenue that cleared Wall Street's bar while earnings fell short, as the company's explosive Attruby commercial launch collided with the heavy costs of building a multi-product genetic medici… Read more BridgeBio Pharma delivered a mixed Q3 2025 report, posting revenue that cleared Wall Street's bar while earnings fell short, as the company's explosive Attruby commercial launch collided with the heavy costs of building a multi-product genetic medicine franchise. Revenue surged to $120.70 million, a staggering 4,318% jump year-over-year and well above the $105.67 million consensus, driven almost entirely by $108.11 million in U.S. Net product sales of Attruby for ATTR-CM, a drug that generated zero revenue in the year-ago period. On the bottom line, however, BridgeBio missed, reporting a loss of $0.95 per share against the $0.78 consensus estimate, a 22.31% shortfall, as SG&A expenses climbed $68.80 million to fund the launch and noncash interest charges on a new royalty monetization deal added $36.41 million in costs. The pipeline simultaneously delivered registrational wins, with BBP-418 and encaleret both meeting Phase 3 primary endpoints; BridgeBio plans NDA filings for both programs in the first half of 2026, a pipeline cadence that echoes momentum seen across rare disease peers this earnings season.

Key Takeaways

  • Strong Attruby commercial launch with 5,259 unique patient prescriptions by 1,355 unique prescribers since FDA approval in November 2024
  • Accelerating growth in treatment-naïve patient segment
  • Attruby clinical differentiation with JACC publication showing cardiovascular outcome benefits within first month of treatment
  • 49% hazard reduction in cardiovascular mortality or recurrent cardiovascular-related hospitalizations at Month 30 versus placebo
  • Royalty revenue from BEYONTTRA sales in EU and Japan
24/7 Wall St

BBIO YoY Financials

Q3 2025 vs Q3 2024, source: SEC Filings

24/7 Wall St

BBIO Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“Attruby's strong commercial performance continues to validate our model, delivering a potential best-in-class medicine to patients who were historically overlooked and building meaningful momentum across all market segments. We are now seeing that same success echoed in our pipeline with home-run data in both ADH1 and LGMD2I/R9, and we continue to advance one of the broadest and fastest-moving portfolios in genetic medicine.”

— Neil Kumar, Q3 2025 Earnings Press Release