Johnson & Johnson
Q4 2025 Earnings
Market Reaction
S&P 500 over the same 30 days: −0.44%.
Did JNJ Beat Earnings? Q4 2025 Results
Johnson & Johnson closed out 2025 on a high note, reporting Q4 revenue of $24.56 billion — up 9.1% year-over-year and ahead of the $24.13 billion Wall Street had expected — while adjusted EPS of $2.46 matched consensus exactly, representing a 20.6% jump from the prior-year period. The standout driver was the Innovative Medicine segment, where oncology powerhouse DARZALEX surged 26.6% to $3.90 billion and TREMFYA soared 67.6% to $1.59 billion, more than offsetting a steep 47.7% decline in STELARA amid biosimilar pressure. MedTech contributed meaningfully as well, with cardiovascular sales climbing 11.5% to $2.30 billion — a gain that comes as J&J makes inroads in electrophysiology, adding competitive pressure on rivals in the pulsed field ablation space. Full-year sales reached $94.19 billion, and management is guiding for roughly $100.50 billion in 2026 revenue alongside adjusted EPS of $11.53 — projections that reflect confidence in a <a href="https://247wallst.com/investing/2026/01/10/the-glp-1-blockbuster-maker-widens-its-lead-as-the-diversified-healthcare-giant-posts-steady-growth/">diversified growth trajectory</a> anchored by oncology momentum and a planned Orthopaedics separation.
- DARZALEX, CARVYKTI, ERLEADA, and RYBREVANT/LAZCLUZE driving Oncology growth
- TREMFYA and SIMPONI/SIMPONI ARIA driving Immunology growth despite STELARA biosimilar erosion
- SPRAVATO and CAPLYTA driving Neuroscience growth
- Electrophysiology products and Abiomed driving MedTech Cardiovascular growth
- Wound closure products driving General Surgery growth
- Shockwave acquisition contributing to MedTech growth
“2025 was a catapult year for Johnson & Johnson, fueled by the strongest portfolio and pipeline in our history”
Johnson & Johnson CEO, on the earnings call
Forward Guidance & Outlook
For full-year 2026, Johnson & Johnson guides for estimated reported sales of approximately $100.5 billion at the midpoint, representing 6.7% growth, and adjusted EPS of $11.53 at midpoint, representing 6.9% growth. The guidance uses an illustrative Euro average rate of $1.17 for January 2026.
JNJ YoY Financials
JNJ Revenue by Segment
JNJ Revenue by Geography
Figures from SEC filings and company reports. Not investment advice.