Phathom Pharmaceuticals

PHAT Q4 2025 Earnings

Reported Feb 26, 2026 at 7:05 AM ET · SEC Source

Q4 25 EPS

$-0.08

BEAT +57.45%

Est. $-0.19

Q4 25 Revenue

$57.6M

BEAT +0.24%

Est. $57.4M

vs S&P Since Q4 25

-25.5%

TRAILING MARKET

PHAT -18.5% vs S&P +6.9%

Full Year 2025 Results

FY 25 EPS

$-2.06

BEAT +11.67%

Est. $-2.33

FY 25 Revenue

$175.1M

BEAT +0.22%

Est. $174.7M

Market Reaction

Did PHAT Beat Earnings? Q4 2025 Results

Phathom Pharmaceuticals delivered a standout fourth quarter, posting a loss of just $0.08 per share against a consensus estimate of $0.42, a beat of 80.95%, while revenue of $57.58 million edged past the $57.20 million estimate and nearly doubled the… Read more Phathom Pharmaceuticals delivered a standout fourth quarter, posting a loss of just $0.08 per share against a consensus estimate of $0.42, a beat of 80.95%, while revenue of $57.58 million edged past the $57.20 million estimate and nearly doubled the year-ago figure, reflecting 94.1% growth year-over-year. The primary engine behind the outperformance was the accelerating commercial launch of VOQUEZNA, which saw approximately 273,000 prescriptions filled in Q4 alone, a 24% sequential increase that has pushed total prescriptions past 1.1 million. Equally notable was the company's expense discipline, with operating costs falling to $55.87 million from $85.27 million in the prior-year quarter, tightening net cash usage to roughly $5.20 million for the period. A $130 million equity offering and a restructured term loan have since bolstered the balance sheet to approximately $190 million in cash, reinforcing management's guidance for FY 2026 net revenues of $320 million to $345 million and operating profitability, excluding stock-based compensation, beginning in Q3 2026, prompting at least one analyst to raise their price target on the stock.

Key Takeaways

  • VOQUEZNA prescriptions grew 24% quarter over quarter to approximately 273,000 in Q4
  • Covered prescriptions grew 21% in Q4 and continue to be the primary driver of revenue
  • Over 1.1 million total VOQUEZNA prescriptions filled to date
  • Operating expense discipline with Q4 operating expenses declining to $55.9 million from $85.3 million year-over-year
  • Net cash usage improved 64% sequentially from approximately $14 million in Q3 to approximately $5.2 million in Q4
24/7 Wall St

PHAT YoY Financials

Q4 2025 vs Q4 2024, source: SEC Filings

24/7 Wall St

PHAT Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“We are pleased with our continued growth throughout 2025, leveraging the efficiency of our GI-focused strategy. Revenue increased significantly over the last three quarters. In the fourth quarter, we realigned our sales organization and enter 2026 with a stronger sales team and marketing initiatives designed to deepen engagement and increase prescribing for GERD across gastroenterologists.”

— Steven Basta, Q4 2025 Earnings Press Release