Arcus Biosciences

Arcus Biosciences (RCUS) Q3 2025 Earnings

Reported Oct 28, 2025 at 4:08 PM ET · SEC Source

Q3 25 EPS

$-1.27

BEAT +1.57%

Est. $-1.29

Q3 25 Revenue

$26.0M

BEAT +28.40%

Est. $20.3M

vs S&P Since Q3 25

+34.8%

BEATING MARKET

RCUS +44.6% vs S&P +9.8%

Market Reaction

Did RCUS Beat Earnings? Q3 2025 Results

Arcus Biosciences delivered a stronger-than-expected third quarter for fiscal 2025, beating both earnings and revenue estimates even as the clinical-stage oncology company absorbed a widening net loss and a sharp year-over-year revenue decline. The c… Read more Arcus Biosciences delivered a stronger-than-expected third quarter for fiscal 2025, beating both earnings and revenue estimates even as the clinical-stage oncology company absorbed a widening net loss and a sharp year-over-year revenue decline. The company posted revenue of $26.00 million, clearing the $20.25 million consensus by 28.40%, while its loss of $1.27 per share came in slightly better than the $1.29 consensus estimate, a 1.57% positive surprise. Revenue fell 45.8% from the year-ago quarter's $48.00 million, a drop largely explained by the absence of a one-time $15.00 million license payment from Taiho's prior-year quemliclustat option exercise and lower Gilead collaboration revenues. Net loss widened to $135.00 million as R&D expenses climbed to $141.00 million, driven by accelerating enrollment in the pivotal PEAK-1 and PRISM-1 trials for casdatifan and quemliclustat. The company ended the quarter with $841.00 million in cash, which management said is sufficient to fund operations through multiple Phase 3 data readouts anticipated across 2026, and guided full-year 2025 revenue of $225.00 million to $235.00 million, with R&D costs expected to ease beginning in Q4.

Key Takeaways

  • Revenue decline driven by absence of prior-year $15 million Taiho license revenue and lower Gilead collaboration revenues
  • R&D expense increase driven by PRISM-1 and PEAK-1 enrollment and start-up activities
  • G&A expense decrease driven by lower stock-based compensation
24/7 Wall St

RCUS YoY Financials

Q3 2025 vs Q3 2024, source: SEC Filings

24/7 Wall St

RCUS Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“Data from the ARC-20 study demonstrate that casdatifan has a best-in-class profile, based on a meaningfully higher response rate and longer PFS relative to data for the only marketed HIF-2a inhibitor. With our global Phase 3 PEAK-1 study now enrolling, and based on the encouraging, emerging data from cohorts evaluating casdatifan-based regimens in early-line settings, we are extremely excited about the potential for casdatifan to be a transformative therapy in clear cell renal cell carcinoma (ccRCC). We remain well capitalized and funded through readout of multiple Phase 3 trials, and we are looking forward to a steady cadence of key data events in 2026 and beyond.”

— Terry Rosen, Q3 2025 Earnings Press Release