Tango Therapeutics

Tango Therapeutics (TNGX) Q2 2025 Earnings

Reported Aug 5, 2025 at 7:06 AM ET · SEC Source

Q2 25 EPS

$-0.35

MISS 1.92%

Est. $-0.34

Q2 25 Revenue

$3.2M

MISS 52.55%

Est. $6.7M

vs S&P Since Q2 25

+344.7%

BEATING MARKET

TNGX +365.0% vs S&P +20.2%

Market Reaction

Did TNGX Beat Earnings? Q2 2025 Results

Tango Therapeutics delivered a disappointing second quarter, missing on both the top and bottom lines as the absence of licensing revenue left a conspicuous gap in its financials. Revenue collapsed 84.0% year-over-year to $3.18 million, falling well … Read more Tango Therapeutics delivered a disappointing second quarter, missing on both the top and bottom lines as the absence of licensing revenue left a conspicuous gap in its financials. Revenue collapsed 84.0% year-over-year to $3.18 million, falling well short of the $6.70 million consensus estimate, a 52.55% miss driven primarily by the lack of any license revenue in the period, compared to the $12.10 million Tango recorded in Q2 2024 when it licensed a drug discovery program to Gilead. The net loss widened to $38.85 million, or $0.35 per share, missing the $0.34 consensus estimate by 1.92%. However, a significant one-time tailwind looms: Tango and Gilead mutually agreed to shorten their collaboration's research term, meaning the remaining $53.80 million in deferred revenue will be recognized in Q3 2025. Looking further ahead, a clinical data update for lead asset TNG462 is expected in the second half of 2025, with a registrational trial in pancreatic cancer targeted for 2026, as the company's $180.80 million cash runway extends into Q1 2027.

Key Takeaways

  • Decreased collaboration revenue due to lower research costs incurred under the Gilead collaboration
  • Absence of license revenue compared to $12.1 million in Q2 2024 from licensing a drug discovery program to Gilead
  • Lower R&D expenses from discontinued programs TNG908 and TNG348, partially offset by increased spend on TNG462, TNG456, and TNG961
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TNGX YoY Financials

Q2 2025 vs Q2 2024, source: SEC Filings

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TNGX Revenue by Segment

With YoY comparisons, source: SEC Filings

Q2 25 Q3 25

“TNG462 has the potential to be a best-in-class PRMT5 inhibitor for the treatment of MTAP-del pancreatic and lung cancers, and we look forward to sharing data that support our conviction later this year.”

— Barbara Weber, Q2 2025 Earnings Press Release