Tango Therapeutics

Tango Therapeutics (TNGX) Q3 2025 Earnings

Reported Nov 4, 2025 at 9:10 AM ET · SEC Source

Q3 25 EPS

$0.13

BEAT +287.32%

Est. $-0.07

Q3 25 Revenue

$53.8M

BEAT +30.47%

Est. $41.2M

vs S&P Since Q3 25

+274.4%

BEATING MARKET

TNGX +285.8% vs S&P +11.4%

Market Reaction

Did TNGX Beat Earnings? Q3 2025 Results

Tango Therapeutics delivered a stunning earnings reversal in Q3 2025, swinging to a profit of $0.13 per diluted share against a consensus estimate of negative $0.07, a beat of 287.32%, while revenue surged 363.6% year over year to $53.81 million, cle… Read more Tango Therapeutics delivered a stunning earnings reversal in Q3 2025, swinging to a profit of $0.13 per diluted share against a consensus estimate of negative $0.07, a beat of 287.32%, while revenue surged 363.6% year over year to $53.81 million, clearing the $41.24 million analyst estimate by 30.47%. The single engine behind those numbers was a one-time accounting event: the truncation of Tango's collaboration agreement with Gilead triggered full recognition of all remaining deferred upfront and research option-extension payments, collapsing what had been a $29.17 million net loss in Q3 2024 into net income of $15.88 million. Crucially, milestones and royalty rights on licensed programs remain intact. Looking ahead, the company enters 2026 with a focused pipeline led by vopimetostat in MTAP-deleted cancers, a pivotal pancreatic cancer trial expected to launch next year, and a cash runway extending into 2028 following a $212 million net-proceeds equity offering completed in October 2025, providing ample runway to reach those catalysts.

Key Takeaways

  • Recognition of all remaining deferred revenue from Gilead collaboration truncation drove Q3 2025 revenue to $53.8 million
  • Reduced R&D expenses from discontinuation of TNG908 and TNG348 programs
  • Lower G&A expenses from decreased personnel-related and external legal/patent costs
24/7 Wall St

TNGX YoY Financials

Q3 2025 vs Q3 2024, source: SEC Filings

24/7 Wall St

TNGX Revenue by Segment

With YoY comparisons, source: SEC Filings

Q2 25 Q3 25

“We are wrapping up 2025 with significant momentum, supported by our recent disclosure of vopimetostat clinical data, supporting the potential of this compound to be a turning point for treatment of multiple difficult-to-treat MTAP-del cancers, beginning with pancreatic cancer.”

— Barbara Weber, Q3 2025 Earnings Press Release