If 2020 was a year Corporate America would like to forget because of the pandemic-induced economic downturn, 2021 is a year business will gladly remember. According to a Bloomberg News story from March 30, 2022, 2021 was the most profitable year for American corporations since 1950. Based on data published by the Commerce Department, profits spiked 35% in 2021, boosted by robust household demand buoyed by government cash transfers.
To identify the Global Fortune 500 companies with skyrocketing profits, 24/7 Wall St. used 2020 and 2021 profit data from Fortune 500. We considered the top 113 international companies in terms of total revenue in 2021 that posted a profit in 2020. Of those, 39 companies reported growing profits.
Of the 39 companies reporting profits on this list, more than one-third were in the health care and FIRE (finance, insurance, and real estate) sectors. Among the health care companies reporting profit in 2021 were HCA Healthcare, UnitedHealth Group, and Cigna. In the FIRE category, Wall Street banks Goldman Sachs and Morgan Stanley were well in the black, as were insurers Allstate, Progressive, and Travelers.
Google and Facebook may have new parent names — Alphabet and Meta Platforms — but they continue to churn out profits. (Find out if Alphabet and Meta are also among the best big companies to work for in 2022.)
Home-improvement companies Lowe’s and Home Depot had a strong year, as homeowners forced to stay home because of COVID-19 found the time to embark on new projects. Similarly, with people still cooking from home more, supermarket companies Kroger, Publix Super Markets, and Albertsons all posted yearly gains. (This company has the most profits per employee.)
Hopes for 2022 being at least as profitable for companies as the previous year are facing serious headwinds, including inflation and Russia’s invasion of Ukraine.
Supply-chain bottlenecks remain, and the rate of inflation, at 8.5% for the 12 months ended March 2022, is the highest since December 1981. This has prompted the Federal Reserve to raise its benchmark interest rate in March for the first time since dropping it to nearly zero two years ago. There may be more increases this year.
During his earnings discussion with Yahoo! Finance on April 20, Procter & Gamble CEO Jon Moeller said commodity costs will cause the consumer company to raise prices. P&G is third on the list with a profit gain of more than 234% in 2021.
The Russia-Ukraine war has sparked a jump in the prices of commodities such as energy, food, and metals that will impact corporate profitability.
Click here to see corporations that made skyrocketing profits in 2021
Source: Stefan Zaklin / Getty Images
39. Freddie Mac
> Profits percent change: 1.6%
> Profits, 2021: $7.33 billion — #27 most in Global 500
> Profits, 2020: $7.21 billion — #32 most in Global 500
> Revenue, 2021: $66.23 billion — #46 most in Global 500
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Source: Tero Vesalainen / iStock via Getty Images
38. Travelers Cos.
> Profits percent change: 2.9%
> Profits, 2021: $2.70 billion — #64 most in Global 500
> Profits, 2020: $2.62 billion — #82 most in Global 500
> Revenue, 2021: $31.98 billion — #95 most in Global 500
Source: Mario Tama / Getty Images News via Getty Images
37. Apple
> Profits percent change: 3.9%
> Profits, 2021: $57.41 billion — #1 most in Global 500
> Profits, 2020: $55.26 billion — #2 most in Global 500
> Revenue, 2021: $274.52 billion — #3 most in Global 500
Source: RiverNorthPhotography / iStock Unreleased via Getty Images
36. Tyson Foods
> Profits percent change: 4.1%
> Profits, 2021: $2.06 billion — #69 most in Global 500
> Profits, 2020: $2.02 billion — #86 most in Global 500
> Revenue, 2021: $43.19 billion — #71 most in Global 500
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Source: JHVEPhoto / iStock Editorial via Getty Images
35. HCA Healthcare
> Profits percent change: 7.1%
> Profits, 2021: $3.75 billion — #50 most in Global 500
> Profits, 2020: $3.51 billion — #67 most in Global 500
> Revenue, 2021: $51.53 billion — #60 most in Global 500
Source: Sundry Photography / iStock Editorial via Getty Images
34. CVS Health
> Profits percent change: 8.2%
> Profits, 2021: $7.18 billion — #28 most in Global 500
> Profits, 2020: $6.63 billion — #38 most in Global 500
> Revenue, 2021: $268.71 billion — #4 most in Global 500
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Source: TrongNguyen / iStock Editorial via Getty Images
33. Costco Wholesale
> Profits percent change: 9.4%
> Profits, 2021: $4.00 billion — #46 most in Global 500
> Profits, 2020: $3.66 billion — #65 most in Global 500
> Revenue, 2021: $166.76 billion — #12 most in Global 500
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Source: JHVEPhoto / iStock Editorial via Getty Images
32. Lockheed Martin
> Profits percent change: 9.7%
> Profits, 2021: $6.83 billion — #31 most in Global 500
> Profits, 2020: $6.23 billion — #40 most in Global 500
> Revenue, 2021: $65.40 billion — #48 most in Global 500
Source: Wolterk / iStock Editorial via Getty Images
31. UnitedHealth Group
> Profits percent change: 11.3%
> Profits, 2021: $15.40 billion — #11 most in Global 500
> Profits, 2020: $13.84 billion — #18 most in Global 500
> Revenue, 2021: $257.14 billion — #5 most in Global 500
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Source: Mario Tama / Getty Images
30. Goldman Sachs Group
> Profits percent change: 11.7%
> Profits, 2021: $9.46 billion — #23 most in Global 500
> Profits, 2020: $8.47 billion — #29 most in Global 500
> Revenue, 2021: $53.50 billion — #57 most in Global 500
Source: Funtay / iStock via Getty Images
29. Philip Morris International
> Profits percent change: 12.1%
> Profits, 2021: $8.06 billion — #25 most in Global 500
> Profits, 2020: $7.19 billion — #34 most in Global 500
> Revenue, 2021: $28.69 billion — #97 most in Global 500
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Source: lcva2 / iStock Editorial via Getty Images
28. Microsoft
> Profits percent change: 12.8%
> Profits, 2021: $44.28 billion — #2 most in Global 500
> Profits, 2020: $39.24 billion — #3 most in Global 500
> Revenue, 2021: $143.01 billion — #15 most in Global 500
Source: Tim Boyle / Getty Images News via Getty Images
27. Home Depot
> Profits percent change: 14.4%
> Profits, 2021: $12.87 billion — #15 most in Global 500
> Profits, 2020: $11.24 billion — #22 most in Global 500
> Revenue, 2021: $132.11 billion — #18 most in Global 500
Source: Brett_Hondow / iStock Editorial via Getty Images
26. Allstate
> Profits percent change: 15.0%
> Profits, 2021: $5.58 billion — #37 most in Global 500
> Profits, 2020: $4.85 billion — #48 most in Global 500
> Revenue, 2021: $44.79 billion — #68 most in Global 500
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Source: Justin Sullivan / Getty Images News via Getty Images
25. Best Buy
> Profits percent change: 16.7%
> Profits, 2021: $1.80 billion — #72 most in Global 500
> Profits, 2020: $1.54 billion — #93 most in Global 500
> Revenue, 2021: $47.26 billion — #64 most in Global 500
Source: 400tmax / iStock Unreleased via Getty Images
24. Alphabet
> Profits percent change: 17.3%
> Profits, 2021: $40.27 billion — #4 most in Global 500
> Profits, 2020: $34.34 billion — #5 most in Global 500
> Revenue, 2021: $182.53 billion — #9 most in Global 500
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Source: / iStock Editorial via Getty Images
23. 3M
> Profits percent change: 17.8%
> Profits, 2021: $5.38 billion — #39 most in Global 500
> Profits, 2020: $4.57 billion — #53 most in Global 500
> Revenue, 2021: $32.18 billion — #93 most in Global 500
Source: Nikada / iStock Unreleased via Getty Images
22. Morgan Stanley
> Profits percent change: 21.6%
> Profits, 2021: $11.00 billion — #19 most in Global 500
> Profits, 2020: $9.04 billion — #27 most in Global 500
> Revenue, 2021: $52.05 billion — #59 most in Global 500
Source: Sundry Photography / iStock Editorial via Getty Images
21. Abbott Laboratories
> Profits percent change: 21.9%
> Profits, 2021: $4.50 billion — #44 most in Global 500
> Profits, 2020: $3.69 billion — #64 most in Global 500
> Revenue, 2021: $34.61 billion — #86 most in Global 500
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Source: wellesenterprises / iStock Editorial via Getty Images
20. Humana
> Profits percent change: 24.4%
> Profits, 2021: $3.37 billion — #53 most in Global 500
> Profits, 2020: $2.71 billion — #80 most in Global 500
> Revenue, 2021: $77.16 billion — #40 most in Global 500
Source: Joe Raedle / Getty Images News via Getty Images
19. Archer Daniels Midland
> Profits percent change: 28.5%
> Profits, 2021: $1.77 billion — #73 most in Global 500
> Profits, 2020: $1.38 billion — #94 most in Global 500
> Revenue, 2021: $64.36 billion — #50 most in Global 500
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Source: JHVEPhoto / iStock Editorial via Getty Images
18. Publix Super Markets
> Profits percent change: 32.2%
> Profits, 2021: $3.97 billion — #47 most in Global 500
> Profits, 2020: $3.01 billion — #77 most in Global 500
> Revenue, 2021: $45.20 billion — #67 most in Global 500
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17. Target
> Profits percent change: 33.1%
> Profits, 2021: $4.37 billion — #45 most in Global 500
> Profits, 2020: $3.28 billion — #71 most in Global 500
> Revenue, 2021: $93.56 billion — #30 most in Global 500
Source: Justin Sullivan / Getty Images News via Getty Images
16. Lowe’s
> Profits percent change: 36.3%
> Profits, 2021: $5.84 billion — #34 most in Global 500
> Profits, 2020: $4.28 billion — #55 most in Global 500
> Revenue, 2021: $89.60 billion — #31 most in Global 500
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Source: Hispanolistic / E+ via Getty Images
15. Centene
> Profits percent change: 36.9%
> Profits, 2021: $1.81 billion — #71 most in Global 500
> Profits, 2020: $1.32 billion — #96 most in Global 500
> Revenue, 2021: $111.11 billion — #24 most in Global 500
Source: Sundry Photography / iStock Editorial via Getty Images
14. Northrop Grumman
> Profits percent change: 41.9%
> Profits, 2021: $3.19 billion — #57 most in Global 500
> Profits, 2020: $2.25 billion — #85 most in Global 500
> Revenue, 2021: $36.80 billion — #83 most in Global 500
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Source: c1a1p1c1o1m1 / iStock via Getty Images
13. Progressive
> Profits percent change: 43.7%
> Profits, 2021: $5.70 billion — #35 most in Global 500
> Profits, 2020: $3.97 billion — #60 most in Global 500
> Revenue, 2021: $42.66 billion — #72 most in Global 500
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Source: jetcityimage / iStock Editorial via Getty Images
12. Dollar General
> Profits percent change: 55.0%
> Profits, 2021: $2.66 billion — #65 most in Global 500
> Profits, 2020: $1.71 billion — #88 most in Global 500
> Revenue, 2021: $33.75 billion — #88 most in Global 500
Source: jetcityimage / iStock Editorial via Getty Images
11. Kroger
> Profits percent change: 55.8%
> Profits, 2021: $2.59 billion — #66 most in Global 500
> Profits, 2020: $1.66 billion — #92 most in Global 500
> Revenue, 2021: $132.50 billion — #17 most in Global 500
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Source: Derick Hudson / iStock Editorial via Getty Images
10. Meta Platforms
> Profits percent change: 57.7%
> Profits, 2021: $29.15 billion — #5 most in Global 500
> Profits, 2020: $18.49 billion — #11 most in Global 500
> Revenue, 2021: $85.97 billion — #34 most in Global 500
Source: Scott Eisen / Getty Images for Patrick Dempsey Center
9. Cigna
> Profits percent change: 65.7%
> Profits, 2021: $8.46 billion — #24 most in Global 500
> Profits, 2020: $5.10 billion — #47 most in Global 500
> Revenue, 2021: $160.40 billion — #13 most in Global 500
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Source: JHVEPhoto / iStock Editorial via Getty Images
8. Thermo Fisher Scientific
> Profits percent change: 72.5%
> Profits, 2021: $6.38 billion — #33 most in Global 500
> Profits, 2020: N/A
> Revenue, 2021: $32.22 billion — #92 most in Global 500
Source: jetcityimage / iStock Editorial via Getty Images
7. Amazon
> Profits percent change: 84.1%
> Profits, 2021: $21.33 billion — #7 most in Global 500
> Profits, 2020: $11.59 billion — #21 most in Global 500
> Revenue, 2021: $386.06 billion — #2 most in Global 500
Source: Jonathunder / Wikimedia Commons
6. Charter Communications
> Profits percent change: 93.2%
> Profits, 2021: $3.22 billion — #56 most in Global 500
> Profits, 2020: $1.67 billion — #91 most in Global 500
> Revenue, 2021: $48.10 billion — #62 most in Global 500
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Source: monsitj / iStock via Getty Images
5. StoneX
> Profits percent change: 99.3%
> Profits, 2021: $0.17 billion — #86 most in Global 500
> Profits, 2020: $85.1 million — #113 most in Global 500
> Revenue, 2021: $54.14 billion — #56 most in Global 500
Source: Teka77 / iStock Editorial via Getty Images
4. FedEx
> Profits percent change: 138.1%
> Profits, 2021: $1.29 billion — #76 most in Global 500
> Profits, 2020: $540.0 million — #106 most in Global 500
> Revenue, 2021: $69.22 billion — #44 most in Global 500
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Source: sharrocks / iStock Unreleased via Getty Images
3. Procter & Gamble
> Profits percent change: 234.3%
> Profits, 2021: $13.03 billion — #14 most in Global 500
> Profits, 2020: $3.90 billion — #61 most in Global 500
> Revenue, 2021: $70.95 billion — #42 most in Global 500
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Source: RiverNorthPhotography / iStock Unreleased via Getty Images
2. Albertsons
> Profits percent change: 255.8%
> Profits, 2021: $466.4 million — #81 most in Global 500
> Profits, 2020: $131.1 million — #112 most in Global 500
> Revenue, 2021: $62.46 billion — #51 most in Global 500
Source: David Tran / iStock Editorial via Getty Images
1. McKesson
> Profits percent change: 2,547.1%
> Profits, 2021: $900.0 million — #78 most in Global 500
> Profits, 2020: $34.0 million — #115 most in Global 500
> Revenue, 2021: $231.05 billion — #7 most in Global 500
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