Source: Sean Rayford / Stringer / Getty Images North America
20. Hammond, LA
> Annual drug deaths, 2019-2021: 52.9 per 100,000 residents
> Total drug deaths, 2019-2021: 215
> Poverty rate: 15.4%
> Population: 135,217
Source: DenisTangneyJr / iStock via Getty Images
19. Bangor, ME
> Annual drug deaths, 2019-2021: 53.2 per 100,000 residents
> Total drug deaths, 2019-2021: 243
> Poverty rate: 16.0%
> Population: 152,765
24/7 Wall St.
Source: shakzu / iStock via Getty Images
18. Vineland-Bridgeton, NJ
> Annual drug deaths, 2019-2021: 53.3 per 100,000 residents
> Total drug deaths, 2019-2021: 240
> Poverty rate: 13.3%
> Population: 153,627
Source: catnap72 / E+ via Getty Images
17. Louisville/Jefferson County, KY-IN
> Annual drug deaths, 2019-2021: 55.4 per 100,000 residents
> Total drug deaths, 2019-2021: 2,116
> Poverty rate: 12.1%
> Population: 1,284,826
Source: Courtesy of Weirton, West Virginia - City Government via Facebook
16. Weirton-Steubenville, WV-OH
> Annual drug deaths, 2019-2021: 55.6 per 100,000 residents
> Total drug deaths, 2019-2021: 193
> Poverty rate: 16.9%
> Population: 113,798
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