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10. New Orleans-Metairie, LA
> Annual drug deaths, 2019-2021: 59.2 per 100,000 residents
> Total drug deaths, 2019-2021: 2,252
> Poverty rate: 18.4%
> Population: 1,261,726
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9. Ocean City, NJ
> Annual drug deaths, 2019-2021: 59.8 per 100,000 residents
> Total drug deaths, 2019-2021: 167
> Poverty rate: 6.7%
> Population: 95,661
24/7 Wall St.
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8. Mansfield, OH
> Annual drug deaths, 2019-2021: 59.9 per 100,000 residents
> Total drug deaths, 2019-2021: 220
> Poverty rate: 12.3%
> Population: 125,195
Source: ChrisBoswell / iStock via Getty Images
7. Atlantic City-Hammonton, NJ
> Annual drug deaths, 2019-2021: 60.4 per 100,000 residents
> Total drug deaths, 2019-2021: 484
> Poverty rate: 15.9%
> Population: 274,966
Source: peeterv / iStock via Getty Images
6. Baltimore-Columbia-Towson, MD
> Annual drug deaths, 2019-2021: 62.9 per 100,000 residents
> Total drug deaths, 2019-2021: 5,307
> Poverty rate: 10.7%
> Population: 2,838,327
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