Apogee Therapeutics is a clinical-stage biotechnology company advancing novel biologics with the potential for differentiated efficacy and dosing profiles in inflammatory and immunology (I&I) markets. The company's pipeline targets well-established mechanisms of action using advanced antibody engineering to optimize half-life and other properties. Its most advanced program, zumilokibart, is being developed for atopic dermatitis (the largest and one of the least penetrated I&I markets), asthma, and eosinophilic esophagitis (EoE). Apogee has five validated targets in its portfolio, pursuing best-in-class efficacy through both monotherapies and combinations of its novel antibodies. Combination programs include APG279 (zumilokibart + APG990) being studied head-to-head versus Dupixent in atopic dermatitis, and APG273 (zumilokibart + APG333), a long-acting IL-13/TSLP combination for respiratory conditions. The company is subject to a pending acquisition by AbbVie for $135.11 per share in cash, expected to close in Q3 2026. Apogee trades on Nasdaq under the ticker APGE. Updated
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Apogee Therapeutics is a clinical-stage biotechnology company advancing novel biologics with the potential for differentiated efficacy and dosing profiles in inflammatory and immunology (I&I) markets.