BioMarin

BioMarin (BMRN) Q2 2025 Earnings

Reported Aug 4, 2025 at 12:04 PM ET · SEC Source

Q2 25 EPS

$1.44

BEAT +42.31%

Est. $1.01

Q2 25 Revenue

$825.4M

BEAT +8.37%

Est. $761.7M

vs S&P Since Q2 25

-28.1%

TRAILING MARKET

BMRN -10.1% vs S&P +18.0%

Market Reaction

Did BMRN Beat Earnings? Q2 2025 Results

BioMarin delivered a standout second quarter for fiscal 2025, posting non-GAAP diluted EPS of $1.44 against a consensus estimate of $1.01, a beat of 42.31%, while revenue of $825.41 million topped expectations by 8.37% and grew 15.9% year-over-year. … Read more BioMarin delivered a standout second quarter for fiscal 2025, posting non-GAAP diluted EPS of $1.44 against a consensus estimate of $1.01, a beat of 42.31%, while revenue of $825.41 million topped expectations by 8.37% and grew 15.9% year-over-year. The driving force behind the results was broad-based portfolio momentum, with VOXZOGO, BioMarin's skeletal condition therapy, generating $221 million in quarterly revenue, up 20% year-over-year, as new patient initiations accelerated across all regions and the drug reached patients in 51 countries. Enzyme Therapies added $555 million, lifted by strong performances from PALYNZIQ and VIMIZIM. Profitability expanded sharply, with non-GAAP operating margin reaching 39.9%. Early Phase 1 data for BMN 333, a potential long-term successor to VOXZOGO, showed encouraging pharmacokinetic results, with a registration-enabling study planned for 2026. Management raised full-year 2025 guidance, now targeting revenue of $3.13 billion to $3.20 billion and non-GAAP diluted EPS of $4.40 to $4.55.

Key Takeaways

  • Strong 20% year-over-year VOXZOGO revenue growth from new patients initiating therapy across all regions
  • Enzyme Therapies revenue growth of 15% driven by increased patient demand and timing of government orders
  • Lower R&D expenses from re-prioritization of investments following 2024 portfolio strategy review
  • Lower SG&A on GAAP basis due to absence of 2024 severance and restructuring costs
  • GAAP operating margin expanded 16.6 percentage points to 33.5%; Non-GAAP operating margin expanded 8.7 percentage points to 39.9%
24/7 Wall St

BMRN YoY Financials

Q2 2025 vs Q2 2024, source: SEC Filings

24/7 Wall St

BMRN Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“We were very pleased with our second quarter performance across all aspects of the business, including strong growth, exciting pipeline progress, and delivery of our business development strategy.”

— Alexander Hardy, Q2 2025 Earnings Press Release