Source: RiverNorthPhotography / iStock Unreleased via Getty Images
35. Toledo, OH
> Annual drug deaths, 2019-2021: 47.6 per 100,000 residents
> Total drug deaths, 2019-2021: 917
> Poverty rate: 15.0%
> Population: 644,217
Source: DenisTangneyJr / iStock via Getty Images
34. Flint, MI
> Annual drug deaths, 2019-2021: 47.7 per 100,000 residents
> Total drug deaths, 2019-2021: 579
> Poverty rate: 16.2%
> Population: 404,208
24/7 Wall St.
Source: Nicholas Smith / iStock via Getty Images
33. Dayton-Kettering, OH
> Annual drug deaths, 2019-2021: 47.7 per 100,000 residents
> Total drug deaths, 2019-2021: 1,159
> Poverty rate: 13.1%
> Population: 813,516
Source: Roberto Michel / iStock Editorial via Getty Images
32. Baton Rouge, LA
> Annual drug deaths, 2019-2021: 47.9 per 100,000 residents
> Total drug deaths, 2019-2021: 1,239
> Poverty rate: 17.0%
> Population: 871,905
Source: DenisTangneyJr / iStock via Getty Images
31. Cumberland, MD-WV
> Annual drug deaths, 2019-2021: 48.2 per 100,000 residents
> Total drug deaths, 2019-2021: 139
> Poverty rate: 13.5%
> Population: 94,586
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