Moderna Sheds $12 Billion in a Single Session After a 14% Drop

As seen on the 24/7 Wall St. homepage on October 22, 2026.

MRNA Moderna

Regular session

1:00pm ET

$205.66

-14.31% open $240.00

A 14.31% slide to $205.67 takes roughly $12 billion off an $84.9 billion biotech in a single session, one of the sharpest single-day drops this name has seen. Keep an eye on whether the $240 open gets reclaimed.

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Moderna held a tight range early before breaking down, closing near $205.67 after opening at $240.

That move erased roughly $12 billion in market value in a single session, concentrating the damage in one large-cap name.

Selling pressure intensified late in the day rather than building gradually, a sign sellers took control into the close.

The $240 open is now the level buyers must reclaim, and it held as resistance across the entire session.

Sources

MRNA company overview

Mentioned: MRNA

Related Market Updates

MRNA Moderna

Oct 20, 6:00pm ET

New 52-week high $242.08 +2.4% vs prior high · 2026-10-15

Moderna just set a fresh 52-week high at $242.08, 2.36% above the peak it reached on October 15. A year ago the stock traded near $27.

Biggest movers · At the close Oct 20, 4:10pm ET

Gainers

GPROGoPro$1.12+7.7%
CLOVClover Health$4.78+7.5%
BILLBill Holdings$48.93+7.1%
MRNAModerna$240.74+6.1%
ARGXargenx$874.58+5.9%

Losers

GMGeneral Motors$76.56-7.5%
GEGE Aerospace$299.39-3.8%
IRENIREN$26.68-3.8%
HWMHowmet Aerospace$211.94-3.7%
PWRQuanta Services$597.07-3.5%

General Motors shed 7.5% into the close, the worst showing across 387 priority names and nearly double the next-biggest decline. GoPro and Clover Health anchored the other end, each up more than 7.5%.

Biggest movers · On the open Oct 19, 9:51am ET

Gainers

GPROGoPro$1.16+10.3%
MRNAModerna$235.83+8.2%
SNDKSanDisk$1,382.56+6.4%
DDOGDatadog$261.02+5.6%
APLDApplied Digital$19.07+5.6%

Losers

HDBHDFC Bank$23.02-3.4%
SESea$90.77-3.2%
BCSBarclays$22.33-2.0%
NFLXNetflix$69.16-1.9%
NGGNational Grid$79.65-1.9%

GoPro's 10.3% jump leads the open, with Moderna close behind and the entire downside capped under 3.5%. Across the priority names, the gains are doing all the work this morning.

52-week highs Oct 16, 6:00pm ET

54 stocks hit new 52-week highs this week

MRNAModerna$218.01+16.2%
BOXBox$39.56+8.9%
SUSuncor Energy$78.05+8.6%
BPBP p.l.c.$50.21+6.9%
SHELShell$106.66+6.5%
DOCUDocuSign$74.65+6.0%
PSXPhillips 66$293.17+5.6%
PBRPetrobras$26+5.3%
PBR-APetrobras$23.3+5.2%
XOMExxon Mobil$178.98+5.1%

54 stocks printed fresh 52-week highs this week, and Big Oil showed up in force: Suncor, BP, Shell, Phillips 66, Petrobras and Exxon all cleared prior peaks. Moderna led the whole list, topping its old high by 16%.

Biggest movers · At the close Oct 14, 4:10pm ET

Gainers

BMYBristol Myers Squibb$59.29+4.6%
UNHUnitedHealth Group$393.7+4.2%
DOCUDocuSign$75.22+4.0%
AZNAstraZeneca$162.05+4.0%
MRNAModerna$224.51+3.8%

Losers

CRWVCoreWeave$65.81-15.4%
DOCNDigitalOcean$109.43-14.7%
CIFRCipher Digital$9.94-12.4%
IRENIren$30.52-12.3%
DELLDell Technologies$505.56-11.7%

Every one of today's five worst performers in a 383-name universe lost double digits, led by CoreWeave's 15.42% drop. The best gain on the other side was capped at 4.62%, so the downside is moving far faster than the upside.

52-week highs Oct 9, 6:00pm ET

36 stocks hit new 52-week highs this week

PBRPetrobras$25.3+16.2%
PEverpure$154.49+15.2%
PBR-APetrobras$22.47+14.8%
HPEHewlett Packard Enterprise$73.46+13.8%
MRNAModerna$225+10.6%
MPCMarathon Petroleum$455.03+9.1%
FTNTFortinet$194.75+8.9%
RBRKRubrik$125.14+8.8%
ITUBItau Unibanco$10.16+8.4%
GTLBGitLab$55.09+7.9%

36 stocks set fresh 52-week highs this week, with Petrobras clearing its old peak by 16%. Hewlett Packard Enterprise, Moderna, Marathon Petroleum, Fortinet, Rubrik and GitLab round out the breakout list.

MRNA Moderna

After-hours

Oct 9, 4:20pm ET

$225.00

+12.56% open $199.89

A 12.6% run to $225 piles roughly $11 billion onto Moderna's $89.8 billion market value in a single session, a move of a size this name rarely posts. Keep an eye on whether the gain holds through the after-hours tape.

Biggest movers · At the close Oct 9, 4:10pm ET

Gainers

MRNAModerna$224.1+13.8%
HIMSHims & Hers$30.89+10.1%
AMTAmerican Tower$181.7+9.0%
DOCNDigitalOcean$134.75+8.8%
ZSZscaler$233.23+7.6%

Losers

TMUST-Mobile US$148.02-13.6%
TAT&T$22.13-11.0%
VZVerizon$41.52-10.4%
JOBYJoby Aviation$5.44-5.5%
FUBOfuboTV$8.87-5.2%

All three major US wireless carriers closed down double digits on the same day, a rare sweep for names usually bought as defensive income. Moderna's 13.8% gain topped the board on the other side.

Reddit Pulse r/wallstreetbets

Oct 9, 1:54pm ET

Another $600k USD gain on $MRNA (total +1.18M USD gain)

u/shanzid01 566 upvotes 100 comments

70k to 1.2M. Living the dream

u/codespyder 302

A $70,000 bet turned into roughly $1.2 million, and the trader is rotating out instead of riding it. The hardest part of a concentrated winner is deciding when to cut the position down.

Biggest movers · At the close Oct 7, 4:11pm ET

Gainers

SPOTSpotify$513.73+5.2%
MRNAModerna$196.4+4.8%
FUBOfuboTV$9.24+4.6%
VSTVistra$166.87+4.0%
MUMicron Technology$1,085.72+3.8%

Losers

GPROGoPro$1.23-7.1%
MSTRMicroStrategy$153.17-6.9%
IRENIren$38.74-6.1%
AAOIApplied Optoelectronics$122.19-6.1%
LCIDLucid$3.91-6.1%

Spotify closed the session's best performer at 5.24%, taking the stock to $513.73. GoPro, MicroStrategy, Iren, Applied Optoelectronics and Lucid all shed more than 6%.

Biggest movers · At the close Oct 6, 4:10pm ET

Gainers

CIENCiena$445.37+14.3%
CEGConstellation Energy$300.52+12.3%
FNFabrinet$488.18+7.6%
NBISNebius Group$250.1+7.5%
ALABAstera Labs$388.9+7.3%

Losers

TEMTempus AI$71.68-14.2%
STXSeagate Technology$806.34-9.1%
MRNAModerna$187.05-8.0%
APPSDigital Turbine$10.48-6.6%
SKHYSK hynix Inc.$182.3-6.5%

Nearly 29 points of spread separated the top and bottom of the board at Monday's close, with Ciena up 14.29% to $445.37 and Tempus AI down 14.21% to $71.68. Four of the five leaders sit in AI infrastructure names.