Gilead Sciences

GILD Q2 2025 Earnings

Reported Aug 7, 2025 at 4:26 PM ET · SEC Source

Q2 25 EPS

$2.01

BEAT +2.72%

Est. $1.96

Q2 25 Revenue

$7.08B

BEAT +1.69%

Est. $6.96B

vs S&P Since Q2 25

-3.9%

TRAILING MARKET

GILD +11.2% vs S&P +15.1%

Market Reaction

Did GILD Beat Earnings? Q2 2025 Results

Gilead Sciences posted a clean beat across the board in Q2 2025, reporting non-GAAP diluted EPS of $2.01 against a consensus estimate of $1.96, a 2.72% positive surprise, while revenue climbed 1.9% year-over-year to $7.08 billion, clearing the $6.96 … Read more Gilead Sciences posted a clean beat across the board in Q2 2025, reporting non-GAAP diluted EPS of $2.01 against a consensus estimate of $1.96, a 2.72% positive surprise, while revenue climbed 1.9% year-over-year to $7.08 billion, clearing the $6.96 billion estimate by 1.69%. The headline driver behind the quarter's strength was HIV, which generated $5.09 billion in sales, up 7% year-over-year, with Biktarvy alone contributing $3.53 billion and Descovy surging 35% to $653 million on favorable pricing and volume. That momentum was partially offset by a steep 44% drop in Veklury to $121 million as COVID-19 hospitalizations declined, a dynamic that also prompted Gilead to trim its full-year Veklury outlook to $1.0 billion. Even so, management raised its full-year non-GAAP EPS guidance to $7.95–$8.25 and lifted product sales guidance to $28.3–$28.7 billion, reflecting confidence in the core franchise. Shares jumped roughly 8.8% following the report, as investors also cheered the FDA approval of Yeztugo, the first twice-yearly HIV prevention option, as a potentially transformative milestone for Gilead's virology business.

Key Takeaways

  • Biktarvy demand growth driving 9% YoY sales increase to $3.5 billion
  • Descovy sales surging 35% YoY on higher average realized price and demand
  • HIV portfolio overall up 7% YoY on increased demand and higher average realized price
  • Trodelvy sales up 14% YoY on higher demand and inventory dynamics
  • Growing demand for Livdelzi and Hepcludex within Liver Disease portfolio
  • Product mix improvement driving non-GAAP product gross margin expansion to 86.9%
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GILD YoY Financials

Q2 2025 vs Q2 2024, source: SEC Filings

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GILD Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26
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GILD Revenue by Geography

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“This was a very successful second quarter for Gilead, including the FDA approval for Yeztugo as the world's first twice-yearly HIV prevention option. Our strong growth this quarter was driven by Biktarvy, Descovy, Trodelvy and Livdelzi, reflecting the diversity of our portfolio. As we enter the third quarter, we are increasing revenue and earnings guidance for the year, and look forward to delivering continued innovation and growth across our core therapeutic areas.”

— Daniel O'Day, Q2 2025 Earnings Press Release