Gilead Sciences

GILD Q4 2025 Earnings

Reported Feb 10, 2026 at 4:02 PM ET · SEC Source

Q4 25 EPS

$1.86

BEAT +1.88%

Est. $1.83

Q4 25 Revenue

$7.93B

BEAT +3.21%

Est. $7.68B

vs S&P Since Q4 25

-19.8%

TRAILING MARKET

GILD -13.8% vs S&P +6.0%

Full Year 2025 Results

FY 25 EPS

$8.15

BEAT +0.40%

Est. $8.12

FY 25 Revenue

$29.44B

BEAT +0.82%

Est. $29.20B

Market Reaction

Did GILD Beat Earnings? Q4 2025 Results

Gilead Sciences capped Q4 2025 with a clean beat on both top and bottom lines, reporting non-GAAP diluted EPS of $1.86 against a consensus estimate of $1.85 while revenue climbed 4.7% year-over-year to $7.92 billion, topping the $7.69 billion analyst… Read more Gilead Sciences capped Q4 2025 with a clean beat on both top and bottom lines, reporting non-GAAP diluted EPS of $1.86 against a consensus estimate of $1.85 while revenue climbed 4.7% year-over-year to $7.92 billion, topping the $7.69 billion analysts had expected. The quarter's strength was anchored in Gilead's HIV and Liver Disease portfolios, with Biktarvy continuing to serve as the company's dominant growth engine and the newly launched Yeztugo, the world's first twice-yearly HIV prevention therapy, adding a fresh commercial catalyst to an already resilient franchise. Higher acquired IPR&D expenses, including $539 million tied to the Interius BioTherapeutics acquisition and Pregene collaboration, weighed on margins but did not derail the broader earnings picture. Separately, Gilead's announced acquisition of Arcellx for up to $7.8 billion signals an accelerating push into oncology that could reshape its long-term revenue mix. Looking ahead, management guided 2026 product sales of $29.60 to $30.00 billion and non-GAAP EPS of $8.45 to $8.85, projecting continued momentum from Yeztugo, Livdelzi, and potential new cancer therapy launches.

Key Takeaways

  • Higher demand for HIV prevention and treatment driving Biktarvy and Descovy growth
  • Successful U.S. launch of Yeztugo, world's first twice-yearly HIV prevention therapy
  • Higher demand for Livdelzi driving Liver Disease portfolio growth
  • Higher Trodelvy demand in breast cancer treatment
  • Lower SG&A expenses from reduced legal and corporate initiative costs
  • Favorable income tax benefits from prior-year tax authority settlement
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GILD YoY Financials

Q4 2025 vs Q4 2024, source: SEC Filings

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GILD Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26
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GILD Revenue by Geography

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“Our fourth quarter and full-year results close out a very strong year for Gilead overall, including the successful U.S. launch of Yeztugo, the world's first twice-yearly HIV prevention therapy, and continued growth for Biktarvy and Descovy.”

— Daniel O'Day, Q4 2025 Earnings Press Release