Gilead Sciences

GILD Q3 2025 Earnings

Reported Oct 30, 2025 at 4:04 PM ET · SEC Source

Q3 25 EPS

$2.47

BEAT +15.67%

Est. $2.14

Q3 25 Revenue

$7.77B

BEAT +4.14%

Est. $7.46B

vs S&P Since Q3 25

-0.2%

TRAILING MARKET

GILD +7.3% vs S&P +7.6%

Market Reaction

Did GILD Beat Earnings? Q3 2025 Results

Gilead Sciences delivered a strong Q3 2025, with non-GAAP diluted EPS of $2.47 clearing the $2.14 consensus by 15.67% and revenue of $7.77 billion beating estimates by 4.14% on 3.0% year-over-year growth. The headline driver was a $400 million royalt… Read more Gilead Sciences delivered a strong Q3 2025, with non-GAAP diluted EPS of $2.47 clearing the $2.14 consensus by 15.67% and revenue of $7.77 billion beating estimates by 4.14% on 3.0% year-over-year growth. The headline driver was a $400 million royalty and contract revenue boost tied to a prior intellectual property sale, though the underlying business showed genuine momentum: the HIV franchise grew 4% to $5.28 billion, anchored by Biktarvy's 6% rise to $3.69 billion, while the liver disease portfolio advanced 12% to $819 million on Livdelzi uptake. Non-GAAP operating margin expanded 729 basis points to 50.5%, underscoring the operating leverage at play. Strategically, Biktarvy patent settlements push generic entry to April 2036, and lenacapavir's strong PrEP approval momentum adds a durable long-term growth layer, much as large-cap pharma peers have leaned on blockbuster franchises to sustain premium valuations. Gilead raised full-year non-GAAP EPS guidance to $8.05-$8.25, reflecting continued confidence in its core portfolio execution.

Key Takeaways

  • Biktarvy sales grew 6% YoY driven by higher demand and favorable inventory dynamics
  • Descovy sales surged 20% YoY on higher demand
  • Livdelzi uptake drove 12% growth in liver disease portfolio
  • Trodelvy sales grew 7% YoY on higher demand
  • Royalty, contract and other revenues increased ~$400M related to a prior IP sale (one-time)
  • Lower acquired IPR&D expenses compared to prior year
  • Higher net unrealized gains on equity investments
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GILD YoY Financials

Q3 2025 vs Q3 2024, source: SEC Filings

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GILD Revenue by Segment

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26
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GILD Revenue by Geography

With YoY comparisons, source: SEC Filings

Q1 25 Q1 26

“We continue to deliver on Gilead's robust portfolio with a strong start for Yeztugo, rapidly growing uptake of Biktarvy, Descovy and Livdelzi, and positive data for Trodelvy in 1L metastatic triple negative breast cancer.”

— Daniel O'Day, Q3 2025 Earnings Press Release