Companies /Healthcare

Ionis Pharmaceuticals Inc

NASDAQ: IONS Biotechnology
$44.00
▲ $0.50 (+1.15%) today
Markets closed · 10:30pm ET

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IONS at a Glance

Valuation
Market cap
$7.2B
Profitability
Revenue (TTM)
$874.1M
Profit margin
-64.7%
EPS (TTM)
$-3.48
Price
52-week range
$43 – $87
Street target
$83.64
Earnings
Next report
Nov 4, 2026
Q2 2026 EPS
$-0.69
vs. $-0.88 est.
+21.4%

Headquartered in Carlsbad, CA Fiscal year ends December NASDAQ: IONS ionis.com

About Ionis Pharmaceuticals

Ionis Pharmaceuticals is a biotechnology company that has pioneered RNA-targeted medicines for over three decades. The company develops and commercializes antisense therapies across neurology, cardiometabolic disease, and other areas of high unmet medical need. Its wholly owned commercial portfolio includes TRYNGOLZA (olezarsen) for severe hypertriglyceridemia, DAWNZERA (donidalorsen) for hereditary angioedema, and a deep pipeline spanning Alexander disease (zilganersen), Angelman syndrome (obudanersen), and next-generation triglyceride-lowering candidates (ION775). Ionis also generates substantial royalty revenue from partnered medicines including SPINRAZA (nusinersen) for spinal muscular atrophy (marketed by Biogen) and WAINUA (eplontersen) for hereditary transthyretin-mediated amyloidosis polyneuropathy (marketed by AstraZeneca). The company earns R&D revenue from collaborative agreements with major pharmaceutical partners including GSK (bepirovirsen for chronic hepatitis B), Novartis (pelacarsen for Lp(a)-driven cardiovascular disease), Biogen, AstraZeneca, and Ono Pharmaceutical. Ionis continues to advance new approaches in gene editing alongside its core RNA therapeutics platform. Updated

IONS Coverage

Frequently Asked Questions

What does Ionis Pharmaceuticals do?

Ionis Pharmaceuticals is a biotechnology company that has pioneered RNA-targeted medicines for over three decades. The company develops and commercializes antisense therapies across neurology, cardiometabolic disease, and other areas of high unmet medical need.

What is the IONS stock price target?

The Wall Street consensus 12-month price target for IONS is $83.64. IONS price prediction →