Headquartered in Miami, FL·Fiscal year ends December·NASDAQ: SMMT·smmttx.com
About Summit Therapeutics
Summit Therapeutics Inc. is a biopharmaceutical oncology company focused on the discovery, development, and commercialization of therapies for serious unmet medical needs in cancer. The company's lead asset is ivonescimab (SMT112), a potential first-in-class bispecific antibody that simultaneously blocks PD-1 (immunotherapy) and VEGF (anti-angiogenesis) in a single molecule, in-licensed from Akeso Inc. in January 2023. Summit holds exclusive rights to develop and commercialize ivonescimab in North America, South America, Europe, the Middle East, Africa, and Japan. The company is currently conducting four global Phase III clinical trials across non-small cell lung cancer and colorectal cancer indications (HARMONi, HARMONi-3, HARMONi-7, and HARMONi-GI3) and has a BLA under FDA review with a PDUFA date of November 14, 2026 for ivonescimab in EGFR-mutated NSCLC post-TKI. Summit has clinical collaborations with GSK, Revolution Medicines, Arcus Biosciences, and GORTEC, and supports over 65 investigator-sponsored trials at institutions including MD Anderson, Memorial Sloan Kettering, and Dana-Farber. The company is pre-revenue and pre-commercial, funding operations through equity offerings. Its shares trade on the Nasdaq Global Market under the symbol SMMT. Updated
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Summit Therapeutics Inc. is a biopharmaceutical oncology company focused on the discovery, development, and commercialization of therapies for serious unmet medical needs in cancer.