Eli Lilly Beat Big and Raised Guidance. Wall Street Sees More Room to Run

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By Vandita Jadeja Published

Quick Read

  • LLY's Q2 EPS beat consensus by 27% and Mounjaro revenue surged 91%, supporting a 12-month price target of $1,427 with 90% model confidence.

  • Merck (MRK) leads peers YTD but lacks a GLP-1 franchise, while AbbVie (ABBV) trails LLY's 98% one-year return by nearly 70 percentage points.

  • Retatrutide's Q1 2027 BLA filing and oral GLP-1 pill Foundayo are near-term catalysts that could push LLY toward the $1,647 bull-case target.

  • Act now: the analyst who called NVIDIA in 2010 just named his top 10 AI stocks — and Eli Lilly didn't make the cut. Grab the names FREE today.

Eli Lilly Beat Big and Raised Guidance. Wall Street Sees More Room to Run

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Eli Lilly (NYSE:LLY | LLY Price Prediction) delivered a monster quarter with revenue growth, a fourth consecutive EPS beat, and a fresh guidance raise. The stock has climbed 9.86% in the past week alone. Our proprietary model sees room to run.

Eli Lilly trades at $1,231.94 as of August 10, 2026. Our 24/7 Wall St. price target is $1,427, implying 15.83% upside over the next twelve months. Our model rates Lilly Bullish, with high confidence at 90%.

An infographic titled
24/7 Wall St.

24/7 Wall St. Price Target Summary

Metric Value
Current Price $1,231.94
24/7 Wall St. Price Target $1,427
Upside 15.83%
Model Rating Bullish
Confidence Level 90%

A Blowout Quarter Reset the Narrative

Lilly is up 15.02% year to date and 98.29% over the past year, sitting just 4% below its 52-week high of $1,249.45.

Q2 revenue landed at $22.97 billion, beating expectations, and EPS of $8.38 came in 27.27% above the $6.5845 consensus. Mounjaro alone did $9.94 billion (+91%), boosted by international growth after China added the drug to its National Reimbursement Drug List. Management raised full-year revenue guidance to $85 to $87 billion and lifted the performance margin range to 49% to 50.5%.

LLY price target

The Case for $1,647 and Higher

Our bull scenario points to $1,646.99, a 33.69% total return. Retatrutide, the next-generation triple-agonist obesity drug with a complete Phase 3 data package and Q1 2027 BLA, drives the thesis.

Layer in Foundayo, the oral GLP-1 pill approved for obesity and submitted for type 2 diabetes, plus VERVE-102’s 62% LDL-C reduction. Wall Street is aligned with 22 buy ratings against just 2 sells, and CEO David Ricks calls Lilly’s future “never been brighter.”

LLY analyst ratings

The Risks Worth Watching

Our bear case suggests $1,167.64, a 5.22% decline. U.S. realized prices fell roughly 9% excluding rebates, and Q2 absorbed $2.78 billion in IPR&D charges from four acquisitions.

Concentration in Mounjaro and Zepbound remains a real risk if a competitor breaks through. Bulls argue the IPR&D hit is non-recurring and pricing pressure is swamped by 60% volume growth. At an implied forward P/E of 39, Lilly needs to keep executing.

How Lilly Compares to Merck and AbbVie

Merck (NYSE:MRK) trades at $130.92 and is up 26.22% YTD, outpacing Lilly. It offers Keytruda-driven oncology exposure at a fraction of Lilly’s multiple, making Lilly’s forward P/E of 39 look demanding. But Merck lacks a GLP-1 franchise growing 91%.

AbbVie (NYSE:ABBV) at $247.97 is up 11.09% YTD, roughly tracking Lilly on a one-month basis but lagging over one year at 29.1% versus Lilly’s 98.29%. AbbVie navigates Humira erosion while Lilly rides a franchise still accelerating. The peer group makes our 24/7 Wall St. price target reasonable: Lilly deserves a premium, but not an unlimited one.

Eli Lilly Price Prediction 2026-2030

The 24/7 Wall St. price target of $1,427 reflects a constructive setup at 90% confidence. The volume-driven growth engine is real, and retatrutide is a near-term catalyst the market has yet to fully price.

The bull thesis strengthens if retatrutide’s BLA stays on track for Q1 2027 and Foundayo scripts ramp cleanly. The thesis weakens if U.S. pricing declines accelerate past the current 9% pace or if payer pushback broadens. For now, momentum plus pipeline wins.

Year 24/7 Wall St. Price Target
2026 $1,300
2027 $1,427
2028 $1,569
2029 $1,725
2030 $1,896

These projections extend our base case annualized return of 9.94% and assume Lilly executes on retatrutide, Foundayo, and manufacturing scale-up. Meaningful deviation could come from GLP-1 competition or a broader pricing reset from U.S. payers.

Contact [email protected] for any questions or corrections.

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About the Author Vandita Jadeja →

Vandita Jadeja is a financial copywriter who loves to read and write about stocks. She believes in buying and holding for long term gains. Her knowledge of words and numbers helps her write clear stock analysis. She has contributed to several publications, including the Joy Wallet, Benzinga, The Motley Fool and InvestorPlace.

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