Special Report

America's Biggest Companies That Didn't Exist 10 Years Ago

2. HPE
> Founding date: Nov. 2015
> Latest annual revenue: $30.9 billion
> Industry: IT

Hewlett Packard Enterprises, or HPE, was formed on Nov. 1, 2015, when it separated from Hewlett Packard. The split was executed so HPE could focus on IT, cloud, and software products and services, while HP stayed with the company’s personal computer and printer business.

HPE beat earnings estimates in each of the last four quarters and reported $30.9 billion in revenue in 2018, up from $28.9 billion in 2017.

Source: Boris Streubel / Getty Images

1. AbbVie
> Founding date: Jan. 2013
> Latest annual revenue: $32.8 billion
> Industry: Pharmaceuticals

Biopharmaceuticals company AbbVie was founded on Jan. 1, 2013, as a spinoff from Abbott Laboratories. While the new Abbott Laboratories would focus on diagnostic and medical devices, AbbVie was founded to focus on research-based pharmaceuticals. Today, AbbVie’s product line includes the rheumatoid arthritis drug Humira — which accounts for 61% of the company’s revenue — as well as the cancer treatment drug Imbruvica and the hepatitis C treatment Mavyret. Abbvie reported $32.8 billion in net revenue in 2018, the 96th largest revenue of any public U.S. company.